Top Biotech Institutional P&L

Estimated portfolio P&L ranking for biotech-focused institutions, based on reported 13F stock holdings. Due to the inherent delay in 13F filings and various factors such as stock split adjustments, this ranking is a best-effort estimate and may contain inaccuracies.

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#Institution1M P&L3M P&LHY P&L

1BAKER BROS. ADVISORS LP-13.67%+11.18%+15.81%

2FARALLON CAPITAL MANAGEMENT LLC-4.09%+11.35%+34.15%

3Avoro Capital Advisors LLC-7.66%+2.44%+18.32%

4RA CAPITAL MANAGEMENT, L.P.-11.31%+6.83%+10.63%

5RTW INVESTMENTS, LP-6.57%+11.51%+27.33%

6DEERFIELD MANAGEMENT COMPANY, L.P.-6.16%+0.58%+11.05%

7PERCEPTIVE ADVISORS LLC-8.20%+11.76%+31.52%

8Paradigm Biocapital Advisors LP-8.51%+14.72%+33.38%

9Deep Track Capital, LP-10.68%+5.41%+24.20%

10ORBIMED ADVISORS LLC-5.78%+8.28%+20.08%

11Bellevue Group AG-8.76%+8.55%+12.35%

12Frazier Life Sciences Management, L.P.-11.36%-0.20%+10.64%

13Darwin Global Management, Ltd.-5.81%+22.17%+1.65%

14SUVRETTA CAPITAL MANAGEMENT, LLC-6.85%-7.50%+6.35%

15Vestal Point Capital, LP-10.43%+7.79%+21.33%

16Siren, L.L.C.-10.48%+6.70%+24.40%

17TCG Crossover Management, LLC-12.90%+7.71%+14.25%

18BVF INC/IL-12.09%+8.76%+27.53%

19BRAIDWELL LP+1.20%+32.07%+62.29%

20Venrock Adviser, LLC-14.58%+12.78%+34.94%

21GILEAD SCIENCES, INC.-19.31%+1.29%+11.08%

22Soleus Capital Management, L.P.-4.11%+7.69%+29.16%

23DeepCurrents Investment Group LLC+948.35%+1023.00%+891.02%

24EcoR1 Capital, LLC-7.56%+12.44%+21.37%

25TANG CAPITAL MANAGEMENT LLC-5.01%+2.53%+18.45%

1BAKER BROS. ADVISORS LP

1M P&L-13.67%

3M P&L+11.18%

HY P&L+15.81%

2FARALLON CAPITAL MANAGEMENT LLC

1M P&L-4.09%

3M P&L+11.35%

HY P&L+34.15%

3Avoro Capital Advisors LLC

1M P&L-7.66%

3M P&L+2.44%

HY P&L+18.32%

4RA CAPITAL MANAGEMENT, L.P.

1M P&L-11.31%

3M P&L+6.83%

HY P&L+10.63%

5RTW INVESTMENTS, LP

1M P&L-6.57%

3M P&L+11.51%

HY P&L+27.33%

6DEERFIELD MANAGEMENT COMPANY, L.P.

1M P&L-6.16%

3M P&L+0.58%

HY P&L+11.05%

7PERCEPTIVE ADVISORS LLC

1M P&L-8.20%

3M P&L+11.76%

HY P&L+31.52%

8Paradigm Biocapital Advisors LP

1M P&L-8.51%

3M P&L+14.72%

HY P&L+33.38%

9Deep Track Capital, LP

1M P&L-10.68%

3M P&L+5.41%

HY P&L+24.20%

10ORBIMED ADVISORS LLC

1M P&L-5.78%

3M P&L+8.28%

HY P&L+20.08%

11Bellevue Group AG

1M P&L-8.76%

3M P&L+8.55%

HY P&L+12.35%

12Frazier Life Sciences Management, L.P.

1M P&L-11.36%

3M P&L-0.20%

HY P&L+10.64%

13Darwin Global Management, Ltd.

1M P&L-5.81%

3M P&L+22.17%

HY P&L+1.65%

14SUVRETTA CAPITAL MANAGEMENT, LLC

1M P&L-6.85%

3M P&L-7.50%

HY P&L+6.35%

15Vestal Point Capital, LP

1M P&L-10.43%

3M P&L+7.79%

HY P&L+21.33%

16Siren, L.L.C.

1M P&L-10.48%

3M P&L+6.70%

HY P&L+24.40%

17TCG Crossover Management, LLC

1M P&L-12.90%

3M P&L+7.71%

HY P&L+14.25%

1M P&L-12.09%

3M P&L+8.76%

HY P&L+27.53%

1M P&L+1.20%

3M P&L+32.07%

HY P&L+62.29%

20Venrock Adviser, LLC

1M P&L-14.58%

3M P&L+12.78%

HY P&L+34.94%

21GILEAD SCIENCES, INC.

1M P&L-19.31%

3M P&L+1.29%

HY P&L+11.08%

22Soleus Capital Management, L.P.

1M P&L-4.11%

3M P&L+7.69%

HY P&L+29.16%

23DeepCurrents Investment Group LLC

1M P&L+948.35%

3M P&L+1023.00%

HY P&L+891.02%

24EcoR1 Capital, LLC

1M P&L-7.56%

3M P&L+12.44%

HY P&L+21.37%

25TANG CAPITAL MANAGEMENT LLC

1M P&L-5.01%

3M P&L+2.53%

HY P&L+18.45%