Top Biotech Institutional P&L

Estimated portfolio P&L ranking for biotech-focused institutions, based on reported 13F stock holdings. Due to the inherent delay in 13F filings and various factors such as stock split adjustments, this ranking is a best-effort estimate and may contain inaccuracies.

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#Institution1M P&L3M P&LHY P&L

1BAKER BROS. ADVISORS LP-8.39%+3.51%-3.64%

2Avoro Capital Advisors LLC-5.53%+8.66%+7.66%

3RTW INVESTMENTS, LP-3.78%+6.44%-3.84%

4RA CAPITAL MANAGEMENT, L.P.-8.81%-4.24%+2.10%

5DEERFIELD MANAGEMENT COMPANY, L.P.-4.95%+2.59%-0.86%

6PERCEPTIVE ADVISORS LLC-7.71%+10.19%+10.79%

7Paradigm Biocapital Advisors LP-5.36%+5.97%+11.48%

8Deep Track Capital, LP+0.47%+5.65%+7.26%

9ORBIMED ADVISORS LLC-1.37%+2.69%-4.66%

10Bellevue Group AG-2.43%-2.37%-7.66%

11Alphabet Inc.+15.50%+33.86%+56.28%

12Frazier Life Sciences Management, L.P.-3.82%+1.82%+6.11%

13Darwin Global Management, Ltd.-16.97%-15.31%-32.33%

14SUVRETTA CAPITAL MANAGEMENT, LLC-1.60%+6.67%+0.40%

15Siren, L.L.C.-3.71%+3.86%+10.55%

16Vestal Point Capital, LP-3.83%+6.86%-0.60%

17TCG Crossover Management, LLC-10.44%+4.58%+15.47%

18BVF INC/IL-4.67%+2.61%+13.65%

19BRAIDWELL LP-1.46%+8.34%-0.79%

20Venrock Adviser, LLC-1.36%+15.69%+33.55%

21TANG CAPITAL MANAGEMENT LLC-4.03%+9.56%+2.19%

22Soleus Capital Management, L.P.-0.36%+11.24%+4.02%

23EcoR1 Capital, LLC-8.33%+8.86%+12.13%

24GILEAD SCIENCES, INC.-5.48%+11.05%-2.92%

25Cormorant Asset Management, LP-6.89%-2.47%+12.89%

1BAKER BROS. ADVISORS LP

1M P&L-8.39%

3M P&L+3.51%

HY P&L-3.64%

2Avoro Capital Advisors LLC

1M P&L-5.53%

3M P&L+8.66%

HY P&L+7.66%

3RTW INVESTMENTS, LP

1M P&L-3.78%

3M P&L+6.44%

HY P&L-3.84%

4RA CAPITAL MANAGEMENT, L.P.

1M P&L-8.81%

3M P&L-4.24%

HY P&L+2.10%

5DEERFIELD MANAGEMENT COMPANY, L.P.

1M P&L-4.95%

3M P&L+2.59%

HY P&L-0.86%

6PERCEPTIVE ADVISORS LLC

1M P&L-7.71%

3M P&L+10.19%

HY P&L+10.79%

7Paradigm Biocapital Advisors LP

1M P&L-5.36%

3M P&L+5.97%

HY P&L+11.48%

8Deep Track Capital, LP

1M P&L+0.47%

3M P&L+5.65%

HY P&L+7.26%

9ORBIMED ADVISORS LLC

1M P&L-1.37%

3M P&L+2.69%

HY P&L-4.66%

10Bellevue Group AG

1M P&L-2.43%

3M P&L-2.37%

HY P&L-7.66%

11Alphabet Inc.

1M P&L+15.50%

3M P&L+33.86%

HY P&L+56.28%

12Frazier Life Sciences Management, L.P.

1M P&L-3.82%

3M P&L+1.82%

HY P&L+6.11%

13Darwin Global Management, Ltd.

1M P&L-16.97%

3M P&L-15.31%

HY P&L-32.33%

14SUVRETTA CAPITAL MANAGEMENT, LLC

1M P&L-1.60%

3M P&L+6.67%

HY P&L+0.40%

15Siren, L.L.C.

1M P&L-3.71%

3M P&L+3.86%

HY P&L+10.55%

16Vestal Point Capital, LP

1M P&L-3.83%

3M P&L+6.86%

HY P&L-0.60%

17TCG Crossover Management, LLC

1M P&L-10.44%

3M P&L+4.58%

HY P&L+15.47%

1M P&L-4.67%

3M P&L+2.61%

HY P&L+13.65%

1M P&L-1.46%

3M P&L+8.34%

HY P&L-0.79%

20Venrock Adviser, LLC

1M P&L-1.36%

3M P&L+15.69%

HY P&L+33.55%

21TANG CAPITAL MANAGEMENT LLC

1M P&L-4.03%

3M P&L+9.56%

HY P&L+2.19%

22Soleus Capital Management, L.P.

1M P&L-0.36%

3M P&L+11.24%

HY P&L+4.02%

23EcoR1 Capital, LLC

1M P&L-8.33%

3M P&L+8.86%

HY P&L+12.13%

24GILEAD SCIENCES, INC.

1M P&L-5.48%

3M P&L+11.05%

HY P&L-2.92%

25Cormorant Asset Management, LP

1M P&L-6.89%

3M P&L-2.47%

HY P&L+12.89%