Top Biotech Institutional P&L

Estimated portfolio P&L ranking for biotech-focused institutions, based on reported 13F stock holdings. Due to the inherent delay in 13F filings and various factors such as stock split adjustments, this ranking is a best-effort estimate and may contain inaccuracies.

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#Institution1M P&L3M P&LHY P&L

1BAKER BROS. ADVISORS LP-3.75%+2.18%+9.81%

2Avoro Capital Advisors LLC-9.81%+0.14%+12.02%

3RTW INVESTMENTS, LP-4.24%+8.72%+22.60%

4RA CAPITAL MANAGEMENT, L.P.-5.13%+0.68%+9.80%

5DEERFIELD MANAGEMENT COMPANY, L.P.-5.58%+2.02%+16.16%

6PERCEPTIVE ADVISORS LLC-4.44%+7.62%+34.94%

7Paradigm Biocapital Advisors LP-3.51%+10.36%+27.56%

8Deep Track Capital, LP-5.97%+13.73%+17.05%

9ORBIMED ADVISORS LLC-8.50%+6.40%+7.60%

10Bellevue Group AG-1.53%+9.74%+7.66%

11Frazier Life Sciences Management, L.P.-8.35%+10.90%+14.52%

12Darwin Global Management, Ltd.-8.38%-14.91%-16.53%

13SUVRETTA CAPITAL MANAGEMENT, LLC-7.86%-2.26%+9.06%

14Siren, L.L.C.-3.55%+11.93%+25.93%

15Vestal Point Capital, LP-3.28%+10.75%+25.30%

16TCG Crossover Management, LLC-4.62%+6.77%+33.37%

17BVF INC/IL-7.49%+8.53%+20.82%

18BRAIDWELL LP+1.15%+30.29%+31.47%

19Venrock Adviser, LLC+1.86%+31.07%+72.68%

20Soleus Capital Management, L.P.-8.27%+5.30%+18.41%

21DeepCurrents Investment Group LLC+0.69%-12.88%-63.07%

22EcoR1 Capital, LLC+6.83%+14.48%+46.70%

23GILEAD SCIENCES, INC.-9.13%+5.06%+36.23%

24Cormorant Asset Management, LP-4.05%+5.13%+17.42%

25TANG CAPITAL MANAGEMENT LLC-8.42%-5.30%+9.91%

1BAKER BROS. ADVISORS LP

1M P&L-3.75%

3M P&L+2.18%

HY P&L+9.81%

2Avoro Capital Advisors LLC

1M P&L-9.81%

3M P&L+0.14%

HY P&L+12.02%

3RTW INVESTMENTS, LP

1M P&L-4.24%

3M P&L+8.72%

HY P&L+22.60%

4RA CAPITAL MANAGEMENT, L.P.

1M P&L-5.13%

3M P&L+0.68%

HY P&L+9.80%

5DEERFIELD MANAGEMENT COMPANY, L.P.

1M P&L-5.58%

3M P&L+2.02%

HY P&L+16.16%

6PERCEPTIVE ADVISORS LLC

1M P&L-4.44%

3M P&L+7.62%

HY P&L+34.94%

7Paradigm Biocapital Advisors LP

1M P&L-3.51%

3M P&L+10.36%

HY P&L+27.56%

8Deep Track Capital, LP

1M P&L-5.97%

3M P&L+13.73%

HY P&L+17.05%

9ORBIMED ADVISORS LLC

1M P&L-8.50%

3M P&L+6.40%

HY P&L+7.60%

10Bellevue Group AG

1M P&L-1.53%

3M P&L+9.74%

HY P&L+7.66%

11Frazier Life Sciences Management, L.P.

1M P&L-8.35%

3M P&L+10.90%

HY P&L+14.52%

12Darwin Global Management, Ltd.

1M P&L-8.38%

3M P&L-14.91%

HY P&L-16.53%

13SUVRETTA CAPITAL MANAGEMENT, LLC

1M P&L-7.86%

3M P&L-2.26%

HY P&L+9.06%

14Siren, L.L.C.

1M P&L-3.55%

3M P&L+11.93%

HY P&L+25.93%

15Vestal Point Capital, LP

1M P&L-3.28%

3M P&L+10.75%

HY P&L+25.30%

16TCG Crossover Management, LLC

1M P&L-4.62%

3M P&L+6.77%

HY P&L+33.37%

1M P&L-7.49%

3M P&L+8.53%

HY P&L+20.82%

1M P&L+1.15%

3M P&L+30.29%

HY P&L+31.47%

19Venrock Adviser, LLC

1M P&L+1.86%

3M P&L+31.07%

HY P&L+72.68%

20Soleus Capital Management, L.P.

1M P&L-8.27%

3M P&L+5.30%

HY P&L+18.41%

21DeepCurrents Investment Group LLC

1M P&L+0.69%

3M P&L-12.88%

HY P&L-63.07%

22EcoR1 Capital, LLC

1M P&L+6.83%

3M P&L+14.48%

HY P&L+46.70%

23GILEAD SCIENCES, INC.

1M P&L-9.13%

3M P&L+5.06%

HY P&L+36.23%

24Cormorant Asset Management, LP

1M P&L-4.05%

3M P&L+5.13%

HY P&L+17.42%

25TANG CAPITAL MANAGEMENT LLC

1M P&L-8.42%

3M P&L-5.30%

HY P&L+9.91%