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The Analysis of VR Adviser, LLC's Holdings & P&L

Currently, VR Adviser, LLC holds 27 types of securities in its portfolio with a total value $2.0B. In the most recent quarter, they have increased their positions in SYRE (+1.0M shares, valued at $32.8M), CYBN (+3.8M shares, valued at $31.4M), VOR (+1.4M shares, valued at $18.9M); decreased their positions in COGT (-2.0M shares, valued at $71.0M), OCUL (-5.8M shares, valued at $71.0M), ORIC (-920.7K shares, valued at $7.5M); initiated new positions in CYBN (+3.8M shares, valued at $31.4M).

1M P&L

+662.0M+31.31%

3M P&L

+629.8M+29.34%

HY P&L

+1.2B+80.52%

P&L figures are estimated based on reported 13F stock holdings and market price changes. They are approximations and may not reflect actual fund performance. Stock split events may also affect the accuracy of these calculations, and we cannot guarantee that all splits have been fully accounted for.

Top Holding Treemap

Top Industries by Value

1Biotechnology1.9B

100.0%

Top Industries by Stock Count

1Biotechnology23 stocks

100.0%

Sponsored

Stock Holdings

TickerCompany NameSharesShares △%Event DateReport DateHistory

APGE APOGEE THERAPEUTICS INC8.5M shares0.00%2025-12-312026-02-17

ORKA ORUKA THERAPEUTICS INC4.1M shares0.00%2025-12-312026-02-17

VRDN VIRIDIAN THERAPEUTICS INC3.9M shares0.00%2025-12-312026-02-17

SYRE SPYRE THERAPEUTICS INC3.7M shares37.24%2025-12-312026-02-17

KALV KALVISTA PHARMACEUTICALS INC6.7M shares0.00%2025-12-312026-02-17

OCUL OCULAR THERAPEUTIX INC7.3M shares-44.42%2025-12-312026-02-17

SVRA SAVARA INC13.7M shares8.35%2025-12-312026-02-17

COGT COGENT BIOSCIENCES INC2.0M shares-50.00%2025-12-312026-02-17

Sponsored

ERAS ERASCA INC17.9M shares0.00%2025-12-312026-02-17

CTMX CYTOMX THERAPEUTICS INC15.6M shares0.00%2025-12-312026-02-17

MAZE MAZE THERAPEUTICS INC1.5M shares25.82%2025-12-312026-02-17

JBIO JADE BIOSCIENCES INC3.2M shares0.00%2025-12-312026-02-17

ELVN ENLIVEN THERAPEUTICS INC3.2M shares0.00%2025-12-312026-02-17

ORIC ORIC PHARMACEUTICALS INC5.7M shares-13.96%2025-12-312026-02-17

ENGENE HOLDINGS INC ENGENE HOLDINGS INC4.8M shares-5.45%2025-12-312026-02-17

DYN DYNE THERAPEUTICS INC2.2M shares0.00%2025-12-312026-02-17

Sponsored

DNTH DIANTHUS THERAPEUTICS INC1.0M shares4.08%2025-12-312026-02-17

UPB UPSTREAM BIO INC1.2M shares0.00%2025-12-312026-02-17

CYBN CYBIN INC3.8M sharesnew addition2025-12-312026-02-17

ZURA ZURA BIO LTD5.3M shares15.41%2025-12-312026-02-17

VOR VOR BIOPHARMA INC1.9M shares288.78%2025-12-312026-02-17

CRESCENT BIOPHARMA INC. CRESCENT BIOPHARMA INC.2.1M shares53.73%2025-12-312026-02-17

SEPN SEPTERNA INC610.8K shares0.00%2025-12-312026-02-17

SURROZEN INC SURROZEN INC632.9K shares0.00%2025-12-312026-02-17

Sponsored

CGEM CULLINAN THERAPEUTICS INC1.4M shares0.00%2025-12-312026-02-17

ARTV ARTIVA BIOTHERAPEUTICS INC1.6M shares0.00%2025-12-312026-02-17

CASI PHARMACEUTICALS INC CASI PHARMACEUTICALS INC987.3K shares0.00%2025-12-312026-02-17

APGE

APOGEE THERAPEUTICS INC

0.00%

Shares8.5M

Event2025-12-31

Filed2026-02-17

ORKA

ORUKA THERAPEUTICS INC

0.00%

Shares4.1M

Event2025-12-31

Filed2026-02-17

VRDN

VIRIDIAN THERAPEUTICS INC

0.00%

Shares3.9M

Event2025-12-31

Filed2026-02-17

SYRE

SPYRE THERAPEUTICS INC

37.24%

Shares3.7M

Event2025-12-31

Filed2026-02-17

KALV

KALVISTA PHARMACEUTICALS INC

0.00%

Shares6.7M

Event2025-12-31

Filed2026-02-17

OCUL

OCULAR THERAPEUTIX INC

-44.42%

Shares7.3M

Event2025-12-31

Filed2026-02-17

SVRA

SAVARA INC

8.35%

Shares13.7M

Event2025-12-31

Filed2026-02-17

COGT

COGENT BIOSCIENCES INC

-50.00%

Shares2.0M

Event2025-12-31

Filed2026-02-17

ERAS

ERASCA INC

0.00%

Shares17.9M

Event2025-12-31

Filed2026-02-17

CTMX

CYTOMX THERAPEUTICS INC

0.00%

Shares15.6M

Event2025-12-31

Filed2026-02-17

MAZE

MAZE THERAPEUTICS INC

25.82%

Shares1.5M

Event2025-12-31

Filed2026-02-17

JBIO

JADE BIOSCIENCES INC

0.00%

Shares3.2M

Event2025-12-31

Filed2026-02-17

ELVN

ENLIVEN THERAPEUTICS INC

0.00%

Shares3.2M

Event2025-12-31

Filed2026-02-17

ORIC

ORIC PHARMACEUTICALS INC

-13.96%

Shares5.7M

Event2025-12-31

Filed2026-02-17

ENGENE HOLDINGS INC

-5.45%

Shares4.8M

Event2025-12-31

Filed2026-02-17

DYN

DYNE THERAPEUTICS INC

0.00%

Shares2.2M

Event2025-12-31

Filed2026-02-17

DNTH

DIANTHUS THERAPEUTICS INC

4.08%

Shares1.0M

Event2025-12-31

Filed2026-02-17

UPB

UPSTREAM BIO INC

0.00%

Shares1.2M

Event2025-12-31

Filed2026-02-17

CYBN

CYBIN INC

New

Shares3.8M

Event2025-12-31

Filed2026-02-17

ZURA

ZURA BIO LTD

15.41%

Shares5.3M

Event2025-12-31

Filed2026-02-17

VOR

VOR BIOPHARMA INC

288.78%

Shares1.9M

Event2025-12-31

Filed2026-02-17

CRESCENT BIOPHARMA INC.

53.73%

Shares2.1M

Event2025-12-31

Filed2026-02-17

SEPN

SEPTERNA INC

0.00%

Shares610.8K

Event2025-12-31

Filed2026-02-17

SURROZEN INC

0.00%

Shares632.9K

Event2025-12-31

Filed2026-02-17

CGEM

CULLINAN THERAPEUTICS INC

0.00%

Shares1.4M

Event2025-12-31

Filed2026-02-17

ARTV

ARTIVA BIOTHERAPEUTICS INC

0.00%

Shares1.6M

Event2025-12-31

Filed2026-02-17

CASI PHARMACEUTICALS INC

0.00%

Shares987.3K

Event2025-12-31

Filed2026-02-17

Call Option Holdings

No call option holdings data available

Put Option Holdings

No put option holdings data available

VR Adviser, LLC Institutional Holdings, Portfolio & P&L — TradeFomo