Sponsored

The Analysis of DEERFIELD MANAGEMENT COMPANY, L.P.'s Holdings & P&L

Currently, DEERFIELD MANAGEMENT COMPANY, L.P. holds 82 types of securities in its portfolio with a total value $8.5B. In the most recent quarter, they have increased their positions in N/A (+200.0M shares, valued at $207.2M), N/A (+3.1M shares, valued at $94.4M), SNDX (+3.8M shares, valued at $88.3M); decreased their positions in NBIX (-574.3K shares, valued at $75.7M), RVMD (-597.6K shares, valued at $58.1M), CPRX (-967.6K shares, valued at $24.0M); initiated new positions in N/A (+200.0M shares, valued at $207.2M), N/A (+3.1M shares, valued at $94.4M), SNDX (+3.8M shares, valued at $88.3M).

1M P&L

-362.9M-5.37%

3M P&L

+26.5M+0.42%

HY P&L

-195.9M-2.97%

P&L figures are estimated based on reported 13F stock holdings and market price changes. They are approximations and may not reflect actual fund performance. Stock split events may also affect the accuracy of these calculations, and we cannot guarantee that all splits have been fully accounted for.

Top Holding Treemap

Top Industries by Value

1Biotechnology4.6B

69.7%

2Drug Manufacturers - Specialty & Generic830.3M

12.6%

3Medical Devices353.4M

5.4%

Top Industries by Stock Count

1Biotechnology37 stocks

57.8%

2Medical Devices5 stocks

7.8%

3Drug Manufacturers - Specialty & Generic5 stocks

7.8%

Sponsored

Stock Holdings

TickerCompany NameSharesShares △%Event DateReport DateHistory

NUVL NUVALENT INC17.2M shares0.00%2026-03-312026-05-15

BROOKDALE SR LIVING INC BROOKDALE SR LIVING INC306.9M shares0.00%2026-03-312026-05-15

COGT COGENT BIOSCIENCES INC9.0M shares0.00%2026-03-312026-05-15

PRAXIS PRECISION MEDICINES I PRAXIS PRECISION MEDICINES I963.4K shares6.64%2026-03-312026-05-15

VTRS VIATRIS INC20.2M shares0.00%2026-03-312026-05-15

UTHR UNITED THERAPEUTICS CORP DEL457.0K shares7.28%2026-03-312026-05-15

RVMD REVOLUTION MEDICINES INC2.3M shares-20.65%2026-03-312026-05-15

MIRUM PHARMACEUTICALS INC MIRUM PHARMACEUTICALS INC70.0M shares0.00%2026-03-312026-05-15

Sponsored

ARROWHEAD PHARMACEUTICALS IN ARROWHEAD PHARMACEUTICALS IN200.0M sharesnew addition2026-03-312026-05-15

CELC CELCUITY INC1.7M shares0.00%2026-03-312026-05-15

CNC CENTENE CORP DEL5.9M shares-8.23%2026-03-312026-05-15

LRMR LARIMAR THERAPEUTICS INC35.6M shares16.34%2026-03-312026-05-15

BKD BROOKDALE SR LIVING INC11.6M shares0.00%2026-03-312026-05-15

VERA VERA THERAPEUTICS INC3.7M shares-8.32%2026-03-312026-05-15

IONS IONIS PHARMACEUTICALS INC2.0M shares0.00%2026-03-312026-05-15

BCRX BIOCRYST PHARMACEUTICALS INC15.0M shares4.86%2026-03-312026-05-15

Sponsored

INSP INSPIRE MED SYS INC2.7M shares79.51%2026-03-312026-05-15

LEGN LEGEND BIOTECH CORP7.7M shares29.60%2026-03-312026-05-15

AHCO ADAPTHEALTH CORP11.5M shares0.00%2026-03-312026-05-15

NAMS NEWAMSTERDAM PHARMA COMPANY4.3M shares2.40%2026-03-312026-05-15

ACHC ACADIA HEALTHCARE COMPANY IN4.5M shares0.00%2026-03-312026-05-15

ARROWHEAD PHARMACEUTICALS IN ARROWHEAD PHARMACEUTICALS IN1.6M shares-14.17%2026-03-312026-05-15

CPRX CATALYST PHARMACEUTICALS INC3.9M shares-19.70%2026-03-312026-05-15

INDIVIOR PHARMACEUTICALS INC INDIVIOR PHARMACEUTICALS INC3.1M sharesnew addition2026-03-312026-05-15

Sponsored

XENE XENON PHARMACEUTICALS INC1.6M shares198.09%2026-03-312026-05-15

IONIS PHARMACEUTICALS INC IONIS PHARMACEUTICALS INC60.0M shares0.00%2026-03-312026-05-15

PHVS PHARVARIS N V3.1M shares0.00%2026-03-312026-05-15

SNDX SYNDAX PHARMACEUTICALS INC3.8M sharesnew addition2026-03-312026-05-15

TNGX TANGO THERAPEUTICS INC4.1M shares42.65%2026-03-312026-05-15

ALIGNMENT HEALTHCARE INC ALIGNMENT HEALTHCARE INC61.0M shares0.00%2026-03-312026-05-15

DNTH DIANTHUS THERAPEUTICS INC1.0M sharesnew addition2026-03-312026-05-15

PFE PFIZER INC3.0M sharesnew addition2026-03-312026-05-15

Sponsored

NBIX NEUROCRINE BIOSCIENCES INC610.0K shares-48.49%2026-03-312026-05-15

DAWN DAY ONE BIOPHARMACEUTICALS I3.7M shares0.00%2026-03-312026-05-15

SVRA SAVARA INC13.6M shares0.00%2026-03-312026-05-15

ZENAS BIOPHARMA INC ZENAS BIOPHARMA INC65.0M sharesnew addition2026-03-312026-05-15

EHAB ENHABIT INC4.7M shares0.00%2026-03-312026-05-15

NEOGENOMICS INC NEOGENOMICS INC72.7M shares0.00%2026-03-312026-05-15

GMAB GENMAB A/S2.5M sharesnew addition2026-03-312026-05-15

BIO BIO RAD LABS INC226.1K shares0.00%2026-03-312026-05-15

Sponsored

LNTH LANTHEUS HLDGS INC828.0K shares0.00%2026-03-312026-05-15

SPRY ARS PHARMACEUTICALS INC7.5M shares0.00%2026-03-312026-05-15

STOK STOKE THERAPEUTICS INC1.8M shares0.00%2026-03-312026-05-15

NVST ENVISTA HOLDINGS CORPORATION2.2M shares-3.09%2026-03-312026-05-15

IDYA IDEAYA BIOSCIENCES INC1.5M shares-28.94%2026-03-312026-05-15

BLTE BELITE BIO INC304.0K shares30.02%2026-03-312026-05-15

BMRN BIOMARIN PHARMACEUTICAL INC851.6K sharesnew addition2026-03-312026-05-15

KYMR KYMERA THERAPEUTICS INC561.2K shares0.00%2026-03-312026-05-15

Sponsored

CERT CERTARA INC7.8M shares0.00%2026-03-312026-05-15

BRIDGEBIO ONCOLOGY THERAPEUT BRIDGEBIO ONCOLOGY THERAPEUT4.9M shares0.00%2026-03-312026-05-15

IRON DISC MEDICINE INC657.0K shares28.53%2026-03-312026-05-15

LIVANOVA PLC LIVANOVA PLC34.3M shares0.00%2026-03-312026-05-15

SION SIONNA THERAPEUTICS INC970.6K shares0.00%2026-03-312026-05-15

CDNA CAREDX INC2.2M shares0.00%2026-03-312026-05-15

GPCR STRUCTURE THERAPEUTICS INC768.0K shares0.00%2026-03-312026-05-15

IMMUNOCORE HLDGS PLC IMMUNOCORE HLDGS PLC30.0M shares0.00%2026-03-312026-05-15

Sponsored

VCYT VERACYTE INC726.0K shares0.00%2026-03-312026-05-15

ALNY ALNYLAM PHARMACEUTICALS INC67.9K shares0.00%2026-03-312026-05-15

EMBC EMBECTA CORP2.5M shares-7.89%2026-03-312026-05-15

TYRA TYRA BIOSCIENCES INC549.0K sharesnew addition2026-03-312026-05-15

FHTX FOGHORN THERAPEUTICS INC4.4M shares20.42%2026-03-312026-05-15

BRIGHT MINDS BIOSCIENCES INC BRIGHT MINDS BIOSCIENCES INC283.0K sharesnew addition2026-03-312026-05-15

CMPX COMPASS THERAPEUTICS INC3.6M shares0.00%2026-03-312026-05-15

MONOPAR THERAPEUTICS INC MONOPAR THERAPEUTICS INC323.7K shares89.82%2026-03-312026-05-15

Sponsored

KYTX KYVERNA THERAPEUTICS INC2.0M shares0.00%2026-03-312026-05-15

SPYGLASS PHARMA INC SPYGLASS PHARMA INC550.0K sharesnew addition2026-03-312026-05-15

BBNX BETA BIONICS INC1.3M shares41.11%2026-03-312026-05-15

TSHA TAYSHA GENE THERAPIES INC2.7M shares0.00%2026-03-312026-05-15

TOI THE ONCOLOGY INSTITUTE INC3.4M shares0.00%2026-03-312026-05-15

CGEM CULLINAN THERAPEUTICS INC386.2K shares0.00%2026-03-312026-05-15

ANNX ANNEXON INC583.9K shares0.00%2026-03-312026-05-15

ALEC ALECTOR INC1.1M shares0.00%2026-03-312026-05-15

Sponsored

NAMSW NEWAMSTERDAM PHARMA COMPANY92.8K shares0.00%2026-03-312026-05-15

EW EDWARDS LIFESCIENCES CORP13.7K shares0.00%2026-03-312026-05-15

BIOMX INC BIOMX INC131.3K shares0.00%2026-03-312026-05-15

VERADERMICS INC VERADERMICS INC5.0K sharesnew addition2026-03-312026-05-15

HUM HUMANA INC917 shares0.00%2026-03-312026-05-15

TOIIW THE ONCOLOGY INSTITUTE INC1.3M shares0.00%2026-03-312026-05-15

QSIAW QUANTUM SI INC333.3K shares0.00%2026-03-312026-05-15

PMVP PMV PHARMACEUTICALS INC8.8K shares0.00%2026-03-312026-05-15

Sponsored

SRZNW SURROZEN INC166.7K shares0.00%2026-03-312026-05-15

MYGN MYRIAD GENETICS INC505 shares0.00%2026-03-312026-05-15

NUVL

NUVALENT INC

0.00%

Shares17.2M

Event2026-03-31

Filed2026-05-15

BROOKDALE SR LIVING INC

0.00%

Shares306.9M

Event2026-03-31

Filed2026-05-15

COGT

COGENT BIOSCIENCES INC

0.00%

Shares9.0M

Event2026-03-31

Filed2026-05-15

PRAXIS PRECISION MEDICINES I

6.64%

Shares963.4K

Event2026-03-31

Filed2026-05-15

VTRS

VIATRIS INC

0.00%

Shares20.2M

Event2026-03-31

Filed2026-05-15

UTHR

UNITED THERAPEUTICS CORP DEL

7.28%

Shares457.0K

Event2026-03-31

Filed2026-05-15

RVMD

REVOLUTION MEDICINES INC

-20.65%

Shares2.3M

Event2026-03-31

Filed2026-05-15

MIRUM PHARMACEUTICALS INC

0.00%

Shares70.0M

Event2026-03-31

Filed2026-05-15

ARROWHEAD PHARMACEUTICALS IN

New

Shares200.0M

Event2026-03-31

Filed2026-05-15

CELC

CELCUITY INC

0.00%

Shares1.7M

Event2026-03-31

Filed2026-05-15

CNC

CENTENE CORP DEL

-8.23%

Shares5.9M

Event2026-03-31

Filed2026-05-15

LRMR

LARIMAR THERAPEUTICS INC

16.34%

Shares35.6M

Event2026-03-31

Filed2026-05-15

BKD

BROOKDALE SR LIVING INC

0.00%

Shares11.6M

Event2026-03-31

Filed2026-05-15

VERA

VERA THERAPEUTICS INC

-8.32%

Shares3.7M

Event2026-03-31

Filed2026-05-15

IONS

IONIS PHARMACEUTICALS INC

0.00%

Shares2.0M

Event2026-03-31

Filed2026-05-15

BCRX

BIOCRYST PHARMACEUTICALS INC

4.86%

Shares15.0M

Event2026-03-31

Filed2026-05-15

INSP

INSPIRE MED SYS INC

79.51%

Shares2.7M

Event2026-03-31

Filed2026-05-15

LEGN

LEGEND BIOTECH CORP

29.60%

Shares7.7M

Event2026-03-31

Filed2026-05-15

AHCO

ADAPTHEALTH CORP

0.00%

Shares11.5M

Event2026-03-31

Filed2026-05-15

NAMS

NEWAMSTERDAM PHARMA COMPANY

2.40%

Shares4.3M

Event2026-03-31

Filed2026-05-15

ACHC

ACADIA HEALTHCARE COMPANY IN

0.00%

Shares4.5M

Event2026-03-31

Filed2026-05-15

ARROWHEAD PHARMACEUTICALS IN

-14.17%

Shares1.6M

Event2026-03-31

Filed2026-05-15

CPRX

CATALYST PHARMACEUTICALS INC

-19.70%

Shares3.9M

Event2026-03-31

Filed2026-05-15

INDIVIOR PHARMACEUTICALS INC

New

Shares3.1M

Event2026-03-31

Filed2026-05-15

XENE

XENON PHARMACEUTICALS INC

198.09%

Shares1.6M

Event2026-03-31

Filed2026-05-15

IONIS PHARMACEUTICALS INC

0.00%

Shares60.0M

Event2026-03-31

Filed2026-05-15

PHVS

PHARVARIS N V

0.00%

Shares3.1M

Event2026-03-31

Filed2026-05-15

SNDX

SYNDAX PHARMACEUTICALS INC

New

Shares3.8M

Event2026-03-31

Filed2026-05-15

TNGX

TANGO THERAPEUTICS INC

42.65%

Shares4.1M

Event2026-03-31

Filed2026-05-15

ALIGNMENT HEALTHCARE INC

0.00%

Shares61.0M

Event2026-03-31

Filed2026-05-15

DNTH

DIANTHUS THERAPEUTICS INC

New

Shares1.0M

Event2026-03-31

Filed2026-05-15

PFE

PFIZER INC

New

Shares3.0M

Event2026-03-31

Filed2026-05-15

NBIX

NEUROCRINE BIOSCIENCES INC

-48.49%

Shares610.0K

Event2026-03-31

Filed2026-05-15

DAWN

DAY ONE BIOPHARMACEUTICALS I

0.00%

Shares3.7M

Event2026-03-31

Filed2026-05-15

SVRA

SAVARA INC

0.00%

Shares13.6M

Event2026-03-31

Filed2026-05-15

ZENAS BIOPHARMA INC

New

Shares65.0M

Event2026-03-31

Filed2026-05-15

EHAB

ENHABIT INC

0.00%

Shares4.7M

Event2026-03-31

Filed2026-05-15

NEOGENOMICS INC

0.00%

Shares72.7M

Event2026-03-31

Filed2026-05-15

GMAB

GENMAB A/S

New

Shares2.5M

Event2026-03-31

Filed2026-05-15

BIO

BIO RAD LABS INC

0.00%

Shares226.1K

Event2026-03-31

Filed2026-05-15

LNTH

LANTHEUS HLDGS INC

0.00%

Shares828.0K

Event2026-03-31

Filed2026-05-15

SPRY

ARS PHARMACEUTICALS INC

0.00%

Shares7.5M

Event2026-03-31

Filed2026-05-15

STOK

STOKE THERAPEUTICS INC

0.00%

Shares1.8M

Event2026-03-31

Filed2026-05-15

NVST

ENVISTA HOLDINGS CORPORATION

-3.09%

Shares2.2M

Event2026-03-31

Filed2026-05-15

IDYA

IDEAYA BIOSCIENCES INC

-28.94%

Shares1.5M

Event2026-03-31

Filed2026-05-15

BLTE

BELITE BIO INC

30.02%

Shares304.0K

Event2026-03-31

Filed2026-05-15

BMRN

BIOMARIN PHARMACEUTICAL INC

New

Shares851.6K

Event2026-03-31

Filed2026-05-15

KYMR

KYMERA THERAPEUTICS INC

0.00%

Shares561.2K

Event2026-03-31

Filed2026-05-15

CERT

CERTARA INC

0.00%

Shares7.8M

Event2026-03-31

Filed2026-05-15

BRIDGEBIO ONCOLOGY THERAPEUT

0.00%

Shares4.9M

Event2026-03-31

Filed2026-05-15

IRON

DISC MEDICINE INC

28.53%

Shares657.0K

Event2026-03-31

Filed2026-05-15

LIVANOVA PLC

0.00%

Shares34.3M

Event2026-03-31

Filed2026-05-15

SION

SIONNA THERAPEUTICS INC

0.00%

Shares970.6K

Event2026-03-31

Filed2026-05-15

CDNA

CAREDX INC

0.00%

Shares2.2M

Event2026-03-31

Filed2026-05-15

GPCR

STRUCTURE THERAPEUTICS INC

0.00%

Shares768.0K

Event2026-03-31

Filed2026-05-15

IMMUNOCORE HLDGS PLC

0.00%

Shares30.0M

Event2026-03-31

Filed2026-05-15

VCYT

VERACYTE INC

0.00%

Shares726.0K

Event2026-03-31

Filed2026-05-15

ALNY

ALNYLAM PHARMACEUTICALS INC

0.00%

Shares67.9K

Event2026-03-31

Filed2026-05-15

EMBC

EMBECTA CORP

-7.89%

Shares2.5M

Event2026-03-31

Filed2026-05-15

TYRA

TYRA BIOSCIENCES INC

New

Shares549.0K

Event2026-03-31

Filed2026-05-15

FHTX

FOGHORN THERAPEUTICS INC

20.42%

Shares4.4M

Event2026-03-31

Filed2026-05-15

BRIGHT MINDS BIOSCIENCES INC

New

Shares283.0K

Event2026-03-31

Filed2026-05-15

CMPX

COMPASS THERAPEUTICS INC

0.00%

Shares3.6M

Event2026-03-31

Filed2026-05-15

MONOPAR THERAPEUTICS INC

89.82%

Shares323.7K

Event2026-03-31

Filed2026-05-15

KYTX

KYVERNA THERAPEUTICS INC

0.00%

Shares2.0M

Event2026-03-31

Filed2026-05-15

SPYGLASS PHARMA INC

New

Shares550.0K

Event2026-03-31

Filed2026-05-15

BBNX

BETA BIONICS INC

41.11%

Shares1.3M

Event2026-03-31

Filed2026-05-15

TSHA

TAYSHA GENE THERAPIES INC

0.00%

Shares2.7M

Event2026-03-31

Filed2026-05-15

TOI

THE ONCOLOGY INSTITUTE INC

0.00%

Shares3.4M

Event2026-03-31

Filed2026-05-15

CGEM

CULLINAN THERAPEUTICS INC

0.00%

Shares386.2K

Event2026-03-31

Filed2026-05-15

ANNX

ANNEXON INC

0.00%

Shares583.9K

Event2026-03-31

Filed2026-05-15

ALEC

ALECTOR INC

0.00%

Shares1.1M

Event2026-03-31

Filed2026-05-15

NAMSW

NEWAMSTERDAM PHARMA COMPANY

0.00%

Shares92.8K

Event2026-03-31

Filed2026-05-15

EDWARDS LIFESCIENCES CORP

0.00%

Shares13.7K

Event2026-03-31

Filed2026-05-15

BIOMX INC

0.00%

Shares131.3K

Event2026-03-31

Filed2026-05-15

VERADERMICS INC

New

Shares5.0K

Event2026-03-31

Filed2026-05-15

HUM

HUMANA INC

0.00%

Shares917

Event2026-03-31

Filed2026-05-15

TOIIW

THE ONCOLOGY INSTITUTE INC

0.00%

Shares1.3M

Event2026-03-31

Filed2026-05-15

QSIAW

QUANTUM SI INC

0.00%

Shares333.3K

Event2026-03-31

Filed2026-05-15

PMVP

PMV PHARMACEUTICALS INC

0.00%

Shares8.8K

Event2026-03-31

Filed2026-05-15

SRZNW

SURROZEN INC

0.00%

Shares166.7K

Event2026-03-31

Filed2026-05-15

MYGN

MYRIAD GENETICS INC

0.00%

Shares505

Event2026-03-31

Filed2026-05-15

Call Option Holdings

No call option holdings data available

Put Option Holdings

No put option holdings data available