The Analysis of ORBIMED ADVISORS LLC's Holdings

Currently, ORBIMED ADVISORS LLC holds 99 types of securities in its portfolio with a total value $4.2B. In the most recent quarter, they have increased their positions in DHR (+263.1K shares, valued at $52.2M), UTHR (+114.9K shares, valued at $48.2M), CI (+162.8K shares, valued at $46.9M); decreased their positions in BSX (-383.9K shares, valued at $37.5M), LLY (-36.4K shares, valued at $27.8M), NTRA (-164.1K shares, valued at $26.4M); initiated new positions in DHR (+263.1K shares, valued at $52.2M), UTHR (+114.9K shares, valued at $48.2M), CI (+162.8K shares, valued at $46.9M).

Top Holding Treemap

Stock Holdings

TickerCompany NameSharesShares △%Event DateReport DateHistory

EWTX EDGEWISE THERAPEUTICS INC15.5M shares0.00%2025-09-302025-11-14

BSX BOSTON SCIENTIFIC CORP2.4M shares-13.65%2025-09-302025-11-14

LLY ELI LILLY & CO301.2K shares-10.78%2025-09-302025-11-14

SVA SINOVAC BIOTECH LTD2.7M shares0.00%2025-09-302025-11-14

ELVN ENLIVEN THERAPEUTICS INC8.0M shares0.00%2025-09-302025-11-14

ALNY ALNYLAM PHARMACEUTICALS INC301.6K shares-11.79%2025-09-302025-11-14

SYK STRYKER CORPORATION359.2K shares0.00%2025-09-302025-11-14

EW EDWARDS LIFESCIENCES CORP1.7M shares-1.41%2025-09-302025-11-14

Sponsored

ISRG INTUITIVE SURGICAL INC287.2K shares-1.31%2025-09-302025-11-14

ARGX ARGENX SE172.3K shares-17.16%2025-09-302025-11-14

SION SIONNA THERAPEUTICS INC3.7M shares0.00%2025-09-302025-11-14

UPB UPSTREAM BIO INC5.7M shares0.00%2025-09-302025-11-14

IRON DISC MEDICINE INC1.4M shares0.00%2025-09-302025-11-14

CAI CARIS LIFE SCIENCES INC3.0M shares0.00%2025-09-302025-11-14

SPRY ARS PHARMACEUTICALS INC8.3M shares0.00%2025-09-302025-11-14

RNA AVIDITY BIOSCIENCES INC1.6M shares-9.60%2025-09-302025-11-14

Sponsored

MBX MBX BIOSCIENCES INC4.0M shares0.00%2025-09-302025-11-14

CGON CG ONCOLOGY INC1.7M shares-8.04%2025-09-302025-11-14

NTRA NATERA INC429.3K shares-27.66%2025-09-302025-11-14

AXSM AXSOME THERAPEUTICS INC531.8K shares24.28%2025-09-302025-11-14

TERN TERNS PHARMACEUTICALS INC7.6M shares0.00%2025-09-302025-11-14

AVBP ARRIVENT BIOPHARMA INC3.0M shares0.00%2025-09-302025-11-14

MLYS MINERALYS THERAPEUTICS INC1.5M shares93.27%2025-09-302025-11-14

EXAS EXACT SCIENCES CORP994.6K shares63.77%2025-09-302025-11-14

Sponsored

CMPX COMPASS THERAPEUTICS INC15.2M shares0.00%2025-09-302025-11-14

CRVS CORVUS PHARMACEUTICALS INC7.2M shares0.00%2025-09-302025-11-14

APLS APELLIS PHARMACEUTICALS INC2.3M shares56.74%2025-09-302025-11-14

DHR DANAHER CORPORATION263.1K sharesnew addition2025-09-302025-11-14

NBIX NEUROCRINE BIOSCIENCES INC353.6K shares-19.36%2025-09-302025-11-14

UTHR UNITED THERAPEUTICS CORP DEL114.9K sharesnew addition2025-09-302025-11-14

CI THE CIGNA GROUP162.8K sharesnew addition2025-09-302025-11-14

CRNX CRINETICS PHARMACEUTICALS IN1.1M shares-4.35%2025-09-302025-11-14

Sponsored

ORIC ORIC PHARMACEUTICALS INC3.6M shares304.96%2025-09-302025-11-14

JANX JANUX THERAPEUTICS INC1.8M shares45.92%2025-09-302025-11-14

ROIV ROIVANT SCIENCES LTD2.7M shares-2.33%2025-09-302025-11-14

ASND ASCENDIS PHARMA A/S191.9K shares457.86%2025-09-302025-11-14

SIBN SI-BONE INC2.6M shares0.00%2025-09-302025-11-14

SCPH SCPHARMACEUTICALS INC6.1M shares0.00%2025-09-302025-11-14

ABVX ABIVAX SA380.0K sharesnew addition2025-09-302025-11-14

GPCR STRUCTURE THERAPEUTICS INC1.1M shares-5.00%2025-09-302025-11-14

Sponsored

TRVI TREVI THERAPEUTICS INC3.3M shares0.00%2025-09-302025-11-14

ITGR INTEGER HLDGS CORP290.0K shares-33.09%2025-09-302025-11-14

DYN DYNE THERAPEUTICS INC2.3M shares124.37%2025-09-302025-11-14

RAPT RAPT THERAPEUTICS INC1.1M shares-33.82%2025-09-302025-11-14

CTMX CYTOMX THERAPEUTICS INC8.5M shares0.00%2025-09-302025-11-14

NPCE NEUROPACE INC2.6M shares0.00%2025-09-302025-11-14

QURE UNIQURE NV458.5K sharesnew addition2025-09-302025-11-14

EYPT EYEPOINT PHARMACEUTICALS INC1.8M sharesnew addition2025-09-302025-11-14

Sponsored

AKRO AKERO THERAPEUTICS INC526.2K shares149.03%2025-09-302025-11-14

ADCT ADC THERAPEUTICS SA5.9M shares0.00%2025-09-302025-11-14

TMO THERMO FISHER SCIENTIFIC INC46.5K shares0.00%2025-09-302025-11-14

RYTM RHYTHM PHARMACEUTICALS INC215.2K shares-13.42%2025-09-302025-11-14

KRYS KRYSTAL BIOTECH INC102.7K shares1016.79%2025-09-302025-11-14

FBRX FORTE BIOSCIENCES INC1.2M shares0.00%2025-09-302025-11-14

AVTX AVALO THERAPEUTICS INC1.3M shares39.53%2025-09-302025-11-14

XENE XENON PHARMACEUTICALS INC419.6K shares-55.73%2025-09-302025-11-14

Sponsored

CARL CARLSMED INC1.3M sharesnew addition2025-09-302025-11-14

KROS KEROS THERAPEUTICS INC1.0M shares0.00%2025-09-302025-11-14

PRLD PRELUDE THERAPEUTICS INC10.9M shares0.00%2025-09-302025-11-14

STTK SHATTUCK LABS INC6.3M sharesnew addition2025-09-302025-11-14

CRBP CORBUS PHARMACEUTICALS HLDGS1.2M shares0.00%2025-09-302025-11-14

URGN UROGEN PHARMA LTD689.0K shares44.02%2025-09-302025-11-14

VIR VIR BIOTECHNOLOGY INC2.4M shares0.00%2025-09-302025-11-14

FOLD AMICUS THERAPEUTICS INC1.6M shares-28.00%2025-09-302025-11-14

Sponsored

IMAGENEBIO INC IMAGENEBIO INC6.2M shares-48.45%2025-09-302025-11-14

TARS TARSUS PHARMACEUTICALS INC197.9K shares0.00%2025-09-302025-11-14

CCCC C4 THERAPEUTICS INC5.2M shares-23.35%2025-09-302025-11-14

CGEM CULLINAN THERAPEUTICS INC1.9M shares0.00%2025-09-302025-11-14

VTGN VISTAGEN THERAPEUTICS INC3.1M sharesnew addition2025-09-302025-11-14

AMLX AMYLYX PHARMACEUTICALS INC750.6K shares139.66%2025-09-302025-11-14

ACET ADICET BIO INC11.4M shares0.00%2025-09-302025-11-14

PMVP PMV PHARMACEUTICALS INC6.0M shares-7.72%2025-09-302025-11-14

Sponsored

WHWK WHITEHAWK THERAPEUTICS INC4.2M shares0.00%2025-09-302025-11-14

VSTM VERASTEM INC887.6K sharesnew addition2025-09-302025-11-14

BTSG BRIGHTSPRING HEALTH SVCS INC263.8K sharesnew addition2025-09-302025-11-14

ALMS ALUMIS INC1.9M shares0.00%2025-09-302025-11-14

BCRX BIOCRYST PHARMACEUTICALS INC901.5K sharesnew addition2025-09-302025-11-14

MIST MILESTONE PHARMACEUTICALS IN3.2M sharesnew addition2025-09-302025-11-14

RPTX REPARE THERAPEUTICS INC3.3M shares0.00%2025-09-302025-11-14

NSPR INSPIREMD INC2.1M shares0.00%2025-09-302025-11-14

Sponsored

BIOA BIOAGE LABS INC790.9K shares-14.22%2025-09-302025-11-14

JBIO JADE BIOSCIENCES INC531.2K shares0.00%2025-09-302025-11-14

QTTB Q32 BIO INC2.3M shares0.00%2025-09-302025-11-14

MNMD MIND MEDICINE MINDMED INC367.8K sharesnew addition2025-09-302025-11-14

CELC CELCUITY INC84.0K sharesnew addition2025-09-302025-11-14

IMTX IMMATICS N.V466.6K shares-35.19%2025-09-302025-11-14

IMA IMAGENEBIO INC378.6K sharesnew addition2025-09-302025-11-14

CELCUITY INC CELCUITY INC2.0M sharesnew addition2025-09-302025-11-14

Sponsored

INSM INSMED INC13.5K shares0.00%2025-09-302025-11-14

ATAI ATAI LIFE SCIENCES NV347.0K sharesnew addition2025-09-302025-11-14

KRRO KORRO BIO INC32.4K shares0.00%2025-09-302025-11-14

MURA MURAL ONCOLOGY PUB LTD CO588.8K shares0.00%2025-09-302025-11-14

TRAW TRAWS PHARMA INC605.5K shares0.00%2025-09-302025-11-14

ANRO ALTO NEUROSCIENCE INC250.0K shares0.00%2025-09-302025-11-14

LYEL LYELL IMMUNOPHARMA INC51.7K shares0.00%2025-09-302025-11-14

KZR KEZAR LIFE SCIENCES INC192.7K shares0.00%2025-09-302025-11-14

Sponsored

XERS XERIS BIOPHARMA HOLDINGS INC80.4K shares0.00%2025-09-302025-11-14

PASG PASSAGE BIO INC59.0K sharesnew addition2025-09-302025-11-14

DHAI DIH HLDG US INC1.9M shares0.00%2025-09-302025-11-14

Call Option Holdings

ABT Call CallABBOTT LABS150.0K sharesnew addition2025-09-302025-11-14

BSX Call CallBOSTON SCIENTIFIC CORP200.0K sharesnew addition2025-09-302025-11-14

PFE Call CallPFIZER INC500.0K sharesnew addition2025-09-302025-11-14

AZN Call CallASTRAZENECA PLC150.0K shares50.00%2025-09-302025-11-14

APLS Call CallAPELLIS PHARMACEUTICALS INC250.0K shares400.00%2025-09-302025-11-14

BTSG Call CallBRIGHTSPRING HEALTH SVCS INC150.0K sharesnew addition2025-09-302025-11-14

SRRK Call CallSCHOLAR ROCK HLDG CORP100.0K sharesnew addition2025-09-302025-11-14

TGTX Call CallTG THERAPEUTICS INC100.0K sharesnew addition2025-09-302025-11-14

VTGN Call CallVISTAGEN THERAPEUTICS INC45.2K sharesnew addition2025-09-302025-11-14

Put Option Holdings

CRNX Put PutCRINETICS PHARMACEUTICALS IN100.0K sharesnew addition2025-09-302025-11-14