Sponsored

The Analysis of RTW INVESTMENTS, LP's Holdings & P&L

Currently, RTW INVESTMENTS, LP holds 89 types of securities in its portfolio with a total value $10.1B. In the most recent quarter, they have increased their positions in MDGL (+2.0M shares, valued at $1.0B), INSM (+4.8M shares, valued at $791.9M), PTGX (+5.1M shares, valued at $533.2M); initiated new positions in MDGL (+2.0M shares, valued at $1.0B), INSM (+4.8M shares, valued at $791.9M), PTGX (+5.1M shares, valued at $533.2M).

1M P&L

-189.1M-1.23%

3M P&L

+80.3M+0.53%

HY P&L

-1.1B-6.79%

P&L figures are estimated based on reported 13F stock holdings and market price changes. They are approximations and may not reflect actual fund performance. Stock split events may also affect the accuracy of these calculations, and we cannot guarantee that all splits have been fully accounted for.

Top Holding Treemap

Top Industries by Value

1Biotechnology8.2B

75.4%

2Medical Devices1.1B

10.1%

3Diagnostics & Research938.5M

8.6%

Top Industries by Stock Count

1Biotechnology77 stocks

72.0%

2Medical Devices9 stocks

8.4%

3Diagnostics & Research8 stocks

7.5%

Sponsored

Stock Holdings

TickerCompany NameSharesShares △%Event DateReport DateHistory

MDGL MADRIGAL PHARMACEUTICALS INC2.0M sharesnew addition2026-03-312026-05-15

INSM INSMED INC4.8M sharesnew addition2026-03-312026-05-15

PTGX PROTAGONIST THERAPEUTICS INC5.1M sharesnew addition2026-03-312026-05-15

PTCT PTC THERAPEUTICS INC7.7M sharesnew addition2026-03-312026-05-15

ARGX ARGENX SE709.4K sharesnew addition2026-03-312026-05-15

CGON CG ONCOLOGY INC7.0M sharesnew addition2026-03-312026-05-15

CELC CELCUITY INC3.0M sharesnew addition2026-03-312026-05-15

TNGX TANGO THERAPEUTICS INC13.3M sharesnew addition2026-03-312026-05-15

Sponsored

ERAS ERASCA INC16.2M sharesnew addition2026-03-312026-05-15

NTRA NATERA INC1.3M sharesnew addition2026-03-312026-05-15

RDNT RADNET INC4.3M sharesnew addition2026-03-312026-05-15

TARS TARSUS PHARMACEUTICALS INC3.3M sharesnew addition2026-03-312026-05-15

APGE APOGEE THERAPEUTICS INC2.8M sharesnew addition2026-03-312026-05-15

SYRE SPYRE THERAPEUTICS INC4.2M sharesnew addition2026-03-312026-05-15

COGT COGENT BIOSCIENCES INC5.5M sharesnew addition2026-03-312026-05-15

IRTC IRHYTHM HOLDINGS INC1.7M sharesnew addition2026-03-312026-05-15

Sponsored

STOK STOKE THERAPEUTICS INC5.6M sharesnew addition2026-03-312026-05-15

CYTK CYTOKINETICS INC2.7M sharesnew addition2026-03-312026-05-15

ACAD ACADIA PHARMACEUTICALS INC7.1M sharesnew addition2026-03-312026-05-15

ESTA ESTABLISHMENT LABS HLDGS INC2.7M sharesnew addition2026-03-312026-05-15

APLS APELLIS PHARMACEUTICALS INC3.7M sharesnew addition2026-03-312026-05-15

IMCR IMMUNOCORE HLDGS PLC4.9M sharesnew addition2026-03-312026-05-15

RGEN REPLIGEN CORP1.2M sharesnew addition2026-03-312026-05-15

NBIX NEUROCRINE BIOSCIENCES INC1.1M sharesnew addition2026-03-312026-05-15

Sponsored

GH GUARDANT HEALTH INC1.5M sharesnew addition2026-03-312026-05-15

IMTX IMMATICS N.V12.9M sharesnew addition2026-03-312026-05-15

ZLAB ZAI LAB LTD6.6M sharesnew addition2026-03-312026-05-15

BLTE BELITE BIO INC715.3K sharesnew addition2026-03-312026-05-15

ISRG INTUITIVE SURGICAL INC220.0K sharesnew addition2026-03-312026-05-15

ORKA ORUKA THERAPEUTICS INC2.1M sharesnew addition2026-03-312026-05-15

GHRS GH RESEARCH PLC5.9M sharesnew addition2026-03-312026-05-15

XNCR XENCOR INC6.8M sharesnew addition2026-03-312026-05-15

Sponsored

URGN UROGEN PHARMA LTD4.5M sharesnew addition2026-03-312026-05-15

CNTA CENTESSA PHARMACEUTICALS PLC2.1M sharesnew addition2026-03-312026-05-15

IMVT IMMUNOVANT INC3.2M sharesnew addition2026-03-312026-05-15

RARE ULTRAGENYX PHARMACEUTICAL IN3.6M sharesnew addition2026-03-312026-05-15

HNGE HINGE HEALTH INC1.9M sharesnew addition2026-03-312026-05-15

CSTL CASTLE BIOSCIENCES INC2.8M sharesnew addition2026-03-312026-05-15

RCKT ROCKET PHARMACEUTICALS INC17.7M sharesnew addition2026-03-312026-05-15

TSHA TAYSHA GENE THERAPIES INC13.7M sharesnew addition2026-03-312026-05-15

Sponsored

ALKS ALKERMES PLC1.7M sharesnew addition2026-03-312026-05-15

CMPS COMPASS PATHWAYS PLC10.6M sharesnew addition2026-03-312026-05-15

KOD KODIAK SCIENCES INC1.5M sharesnew addition2026-03-312026-05-15

REPL REPLIMUNE GROUP INC7.4M sharesnew addition2026-03-312026-05-15

CRNX CRINETICS PHARMACEUTICALS IN1.5M sharesnew addition2026-03-312026-05-15

OBIO 11.9M sharesnew addition2026-04-272026-04-29

QURE UNIQURE NV2.6M sharesnew addition2026-03-312026-05-15

WAY WAYSTAR HLDG CORP1.6M sharesnew addition2026-03-312026-05-15

Sponsored

ARROWHEAD PHARMACEUTICALS IN ARROWHEAD PHARMACEUTICALS IN585.7K sharesnew addition2026-03-312026-05-15

OBIO ORCHESTRA BIOMED HLDGS INC8.3M sharesnew addition2026-03-312026-05-15

VERASTEM INC VERASTEM INC6.6M sharesnew addition2026-03-312026-05-15

EVOMMUNE INC EVOMMUNE INC1.5M sharesnew addition2026-03-312026-05-15

SYK STRYKER CORPORATION100.0K sharesnew addition2026-03-312026-05-15

SVRA SAVARA INC6.0M sharesnew addition2026-03-312026-05-15

CADL CANDEL THERAPEUTICS INC6.4M sharesnew addition2026-03-312026-05-15

AQST AQUESTIVE THERAPEUTICS INC7.4M sharesnew addition2026-03-312026-05-15

Sponsored

AKTIS ONCOLOGY INC AKTIS ONCOLOGY INC1.6M sharesnew addition2026-03-312026-05-15

NGNE NEUROGENE INC1.4M sharesnew addition2026-03-312026-05-15

CGEM CULLINAN THERAPEUTICS INC1.7M sharesnew addition2026-03-312026-05-15

CMPX COMPASS THERAPEUTICS INC4.2M sharesnew addition2026-03-312026-05-15

DNTH DIANTHUS THERAPEUTICS INC248.1K sharesnew addition2026-03-312026-05-15

FLGT FULGENT GENETICS INC1.3M sharesnew addition2026-03-312026-05-15

BBNX BETA BIONICS INC2.0M sharesnew addition2026-03-312026-05-15

KYMR KYMERA THERAPEUTICS INC240.0K sharesnew addition2026-03-312026-05-15

Sponsored

IPSC CENTURY THERAPEUTICS INC8.7M sharesnew addition2026-03-312026-05-15

BEAM BEAM THERAPEUTICS INC570.4K sharesnew addition2026-03-312026-05-15

AVALO THERAPEUTICS INC AVALO THERAPEUTICS INC857.0K sharesnew addition2026-03-312026-05-15

OCGN OCUGEN INC6.7M sharesnew addition2026-03-312026-05-15

HTFL HEARTFLOW INC495.0K sharesnew addition2026-03-312026-05-15

WVE WAVE LIFE SCIENCES LTD1.4M sharesnew addition2026-03-312026-05-15

PCSC PERCEPTIVE CAP SOLUTIONS COR742.5K sharesnew addition2026-03-312026-05-15

JBIO JADE BIOSCIENCES INC573.2K sharesnew addition2026-03-312026-05-15

Sponsored

CAPR CAPRICOR THERAPEUTICS INC250.0K sharesnew addition2026-03-312026-05-15

MIST MILESTONE PHARMACEUTICALS IN6.3M sharesnew addition2026-03-312026-05-15

KLRS KALARIS THERAPEUTICS INC1.3M sharesnew addition2026-03-312026-05-15

IVA INVENTIVA SA1.3M sharesnew addition2026-03-312026-05-15

ATAIBECKLEY INC ATAIBECKLEY INC2.0M sharesnew addition2026-03-312026-05-15

CRESCENT BIOPHARMA INC. CRESCENT BIOPHARMA INC.372.9K sharesnew addition2026-03-312026-05-15

LRMR LARIMAR THERAPEUTICS INC1.5M sharesnew addition2026-03-312026-05-15

TENAX THERAPEUTICS INC TENAX THERAPEUTICS INC370.2K sharesnew addition2026-03-312026-05-15

Sponsored

DEFINIUM THERAPEUTICS INC DEFINIUM THERAPEUTICS INC300.0K sharesnew addition2026-03-312026-05-15

LUMEXA IMAGING HOLDINGS INC LUMEXA IMAGING HOLDINGS INC650.0K sharesnew addition2026-03-312026-05-15

FDMT 4D MOLECULAR THERAPEUTICS IN475.7K sharesnew addition2026-03-312026-05-15

MEDLINE INC MEDLINE INC70.0K sharesnew addition2026-03-312026-05-15

OMDA OMADA HEALTH INC200.0K sharesnew addition2026-03-312026-05-15

IRON DISC MEDICINE INC30.0K sharesnew addition2026-03-312026-05-15

IMA IMAGENEBIO INC334.4K sharesnew addition2026-03-312026-05-15

XGN EXAGEN INC395.2K sharesnew addition2026-03-312026-05-15

Sponsored

RCKTW ROCKET PHARMACEUTICALS INC350.0K sharesnew addition2026-03-312026-05-15

MDGL

MADRIGAL PHARMACEUTICALS INC

New

Shares2.0M

Event2026-03-31

Filed2026-05-15

INSM

INSMED INC

New

Shares4.8M

Event2026-03-31

Filed2026-05-15

PTGX

PROTAGONIST THERAPEUTICS INC

New

Shares5.1M

Event2026-03-31

Filed2026-05-15

PTCT

PTC THERAPEUTICS INC

New

Shares7.7M

Event2026-03-31

Filed2026-05-15

ARGX

ARGENX SE

New

Shares709.4K

Event2026-03-31

Filed2026-05-15

CGON

CG ONCOLOGY INC

New

Shares7.0M

Event2026-03-31

Filed2026-05-15

CELC

CELCUITY INC

New

Shares3.0M

Event2026-03-31

Filed2026-05-15

TNGX

TANGO THERAPEUTICS INC

New

Shares13.3M

Event2026-03-31

Filed2026-05-15

ERAS

ERASCA INC

New

Shares16.2M

Event2026-03-31

Filed2026-05-15

NTRA

NATERA INC

New

Shares1.3M

Event2026-03-31

Filed2026-05-15

RDNT

RADNET INC

New

Shares4.3M

Event2026-03-31

Filed2026-05-15

TARS

TARSUS PHARMACEUTICALS INC

New

Shares3.3M

Event2026-03-31

Filed2026-05-15

APGE

APOGEE THERAPEUTICS INC

New

Shares2.8M

Event2026-03-31

Filed2026-05-15

SYRE

SPYRE THERAPEUTICS INC

New

Shares4.2M

Event2026-03-31

Filed2026-05-15

COGT

COGENT BIOSCIENCES INC

New

Shares5.5M

Event2026-03-31

Filed2026-05-15

IRTC

IRHYTHM HOLDINGS INC

New

Shares1.7M

Event2026-03-31

Filed2026-05-15

STOK

STOKE THERAPEUTICS INC

New

Shares5.6M

Event2026-03-31

Filed2026-05-15

CYTK

CYTOKINETICS INC

New

Shares2.7M

Event2026-03-31

Filed2026-05-15

ACAD

ACADIA PHARMACEUTICALS INC

New

Shares7.1M

Event2026-03-31

Filed2026-05-15

ESTA

ESTABLISHMENT LABS HLDGS INC

New

Shares2.7M

Event2026-03-31

Filed2026-05-15

APLS

APELLIS PHARMACEUTICALS INC

New

Shares3.7M

Event2026-03-31

Filed2026-05-15

IMCR

IMMUNOCORE HLDGS PLC

New

Shares4.9M

Event2026-03-31

Filed2026-05-15

RGEN

REPLIGEN CORP

New

Shares1.2M

Event2026-03-31

Filed2026-05-15

NBIX

NEUROCRINE BIOSCIENCES INC

New

Shares1.1M

Event2026-03-31

Filed2026-05-15

GUARDANT HEALTH INC

New

Shares1.5M

Event2026-03-31

Filed2026-05-15

IMTX

IMMATICS N.V

New

Shares12.9M

Event2026-03-31

Filed2026-05-15

ZLAB

ZAI LAB LTD

New

Shares6.6M

Event2026-03-31

Filed2026-05-15

BLTE

BELITE BIO INC

New

Shares715.3K

Event2026-03-31

Filed2026-05-15

ISRG

INTUITIVE SURGICAL INC

New

Shares220.0K

Event2026-03-31

Filed2026-05-15

ORKA

ORUKA THERAPEUTICS INC

New

Shares2.1M

Event2026-03-31

Filed2026-05-15

GHRS

GH RESEARCH PLC

New

Shares5.9M

Event2026-03-31

Filed2026-05-15

XNCR

XENCOR INC

New

Shares6.8M

Event2026-03-31

Filed2026-05-15

URGN

UROGEN PHARMA LTD

New

Shares4.5M

Event2026-03-31

Filed2026-05-15

CNTA

CENTESSA PHARMACEUTICALS PLC

New

Shares2.1M

Event2026-03-31

Filed2026-05-15

IMVT

IMMUNOVANT INC

New

Shares3.2M

Event2026-03-31

Filed2026-05-15

RARE

ULTRAGENYX PHARMACEUTICAL IN

New

Shares3.6M

Event2026-03-31

Filed2026-05-15

HNGE

HINGE HEALTH INC

New

Shares1.9M

Event2026-03-31

Filed2026-05-15

CSTL

CASTLE BIOSCIENCES INC

New

Shares2.8M

Event2026-03-31

Filed2026-05-15

RCKT

ROCKET PHARMACEUTICALS INC

New

Shares17.7M

Event2026-03-31

Filed2026-05-15

TSHA

TAYSHA GENE THERAPIES INC

New

Shares13.7M

Event2026-03-31

Filed2026-05-15

ALKS

ALKERMES PLC

New

Shares1.7M

Event2026-03-31

Filed2026-05-15

CMPS

COMPASS PATHWAYS PLC

New

Shares10.6M

Event2026-03-31

Filed2026-05-15

KOD

KODIAK SCIENCES INC

New

Shares1.5M

Event2026-03-31

Filed2026-05-15

REPL

REPLIMUNE GROUP INC

New

Shares7.4M

Event2026-03-31

Filed2026-05-15

CRNX

CRINETICS PHARMACEUTICALS IN

New

Shares1.5M

Event2026-03-31

Filed2026-05-15

OBIO

New

Shares11.9M

Event2026-04-27

Filed2026-04-29

QURE

UNIQURE NV

New

Shares2.6M

Event2026-03-31

Filed2026-05-15

WAY

WAYSTAR HLDG CORP

New

Shares1.6M

Event2026-03-31

Filed2026-05-15

ARROWHEAD PHARMACEUTICALS IN

New

Shares585.7K

Event2026-03-31

Filed2026-05-15

OBIO

ORCHESTRA BIOMED HLDGS INC

New

Shares8.3M

Event2026-03-31

Filed2026-05-15

VERASTEM INC

New

Shares6.6M

Event2026-03-31

Filed2026-05-15

EVOMMUNE INC

New

Shares1.5M

Event2026-03-31

Filed2026-05-15

SYK

STRYKER CORPORATION

New

Shares100.0K

Event2026-03-31

Filed2026-05-15

SVRA

SAVARA INC

New

Shares6.0M

Event2026-03-31

Filed2026-05-15

CADL

CANDEL THERAPEUTICS INC

New

Shares6.4M

Event2026-03-31

Filed2026-05-15

AQST

AQUESTIVE THERAPEUTICS INC

New

Shares7.4M

Event2026-03-31

Filed2026-05-15

AKTIS ONCOLOGY INC

New

Shares1.6M

Event2026-03-31

Filed2026-05-15

NGNE

NEUROGENE INC

New

Shares1.4M

Event2026-03-31

Filed2026-05-15

CGEM

CULLINAN THERAPEUTICS INC

New

Shares1.7M

Event2026-03-31

Filed2026-05-15

CMPX

COMPASS THERAPEUTICS INC

New

Shares4.2M

Event2026-03-31

Filed2026-05-15

DNTH

DIANTHUS THERAPEUTICS INC

New

Shares248.1K

Event2026-03-31

Filed2026-05-15

FLGT

FULGENT GENETICS INC

New

Shares1.3M

Event2026-03-31

Filed2026-05-15

BBNX

BETA BIONICS INC

New

Shares2.0M

Event2026-03-31

Filed2026-05-15

KYMR

KYMERA THERAPEUTICS INC

New

Shares240.0K

Event2026-03-31

Filed2026-05-15

IPSC

CENTURY THERAPEUTICS INC

New

Shares8.7M

Event2026-03-31

Filed2026-05-15

BEAM

BEAM THERAPEUTICS INC

New

Shares570.4K

Event2026-03-31

Filed2026-05-15

AVALO THERAPEUTICS INC

New

Shares857.0K

Event2026-03-31

Filed2026-05-15

OCGN

OCUGEN INC

New

Shares6.7M

Event2026-03-31

Filed2026-05-15

HTFL

HEARTFLOW INC

New

Shares495.0K

Event2026-03-31

Filed2026-05-15

WVE

WAVE LIFE SCIENCES LTD

New

Shares1.4M

Event2026-03-31

Filed2026-05-15

PCSC

PERCEPTIVE CAP SOLUTIONS COR

New

Shares742.5K

Event2026-03-31

Filed2026-05-15

JBIO

JADE BIOSCIENCES INC

New

Shares573.2K

Event2026-03-31

Filed2026-05-15

CAPR

CAPRICOR THERAPEUTICS INC

New

Shares250.0K

Event2026-03-31

Filed2026-05-15

MIST

MILESTONE PHARMACEUTICALS IN

New

Shares6.3M

Event2026-03-31

Filed2026-05-15

KLRS

KALARIS THERAPEUTICS INC

New

Shares1.3M

Event2026-03-31

Filed2026-05-15

IVA

INVENTIVA SA

New

Shares1.3M

Event2026-03-31

Filed2026-05-15

ATAIBECKLEY INC

New

Shares2.0M

Event2026-03-31

Filed2026-05-15

CRESCENT BIOPHARMA INC.

New

Shares372.9K

Event2026-03-31

Filed2026-05-15

LRMR

LARIMAR THERAPEUTICS INC

New

Shares1.5M

Event2026-03-31

Filed2026-05-15

TENAX THERAPEUTICS INC

New

Shares370.2K

Event2026-03-31

Filed2026-05-15

DEFINIUM THERAPEUTICS INC

New

Shares300.0K

Event2026-03-31

Filed2026-05-15

LUMEXA IMAGING HOLDINGS INC

New

Shares650.0K

Event2026-03-31

Filed2026-05-15

FDMT

4D MOLECULAR THERAPEUTICS IN

New

Shares475.7K

Event2026-03-31

Filed2026-05-15

MEDLINE INC

New

Shares70.0K

Event2026-03-31

Filed2026-05-15

OMDA

OMADA HEALTH INC

New

Shares200.0K

Event2026-03-31

Filed2026-05-15

IRON

DISC MEDICINE INC

New

Shares30.0K

Event2026-03-31

Filed2026-05-15

IMA

IMAGENEBIO INC

New

Shares334.4K

Event2026-03-31

Filed2026-05-15

XGN

EXAGEN INC

New

Shares395.2K

Event2026-03-31

Filed2026-05-15

RCKTW

ROCKET PHARMACEUTICALS INC

New

Shares350.0K

Event2026-03-31

Filed2026-05-15

Call Option Holdings

No call option holdings data available

Put Option Holdings

No put option holdings data available