The Analysis of BAKER BROS. ADVISORS LP's Holdings
Currently, BAKER BROS. ADVISORS LP holds 91 types of securities in its portfolio with a total value $14.5B. In the most recent quarter, they have increased their positions in CELC (+2.5M shares, valued at $121.8M), KYMR (+2.0M shares, valued at $114.6M), MDGL (+165.7K shares, valued at $76.0M); decreased their positions in INSM (-1.0M shares, valued at $145.4M), GPCR (-952.7K shares, valued at $26.7M), CERS (-2.9M shares, valued at $4.6M); initiated new positions in ABVX (+875.8K shares, valued at $74.4M), N/A (+30.8M shares, valued at $40.9M), IONS (+566.8K shares, valued at $37.1M). Stock Holdings
TickerCompany NameSharesShares âŗ%Event DateReport DateHistory
ONC BeOne Medicines Ltd.8.8M shares0.00%2025-09-302025-11-14
INCY Incyte Corporation30.7M shares0.00%2025-09-302025-11-14 MDGL Madrigal Pharmaceuticals, Inc.2.1M shares8.38%2025-09-302025-11-14 INSM Insmed Incorporated6.7M shares-13.09%2025-09-302025-11-14 ACAD ACADIA Pharmaceuticals Inc.42.9M shares0.00%2025-09-302025-11-14 KYMR Kymera Therapeutics, Inc.8.7M shares30.45%2025-12-092025-12-11 SMMT Summit Therapeutics Inc.33.7M shares0.00%2025-09-302025-11-14 RYTM Rhythm Pharmaceuticals, Inc.5.6M shares0.00%2025-09-302025-11-14 KOD Kodiak Sciences Inc.20.1M shares15.93%2025-12-182025-12-19 RVMD Revolution Medicines, Inc.9.5M shares0.97%2025-09-302025-11-14 CELC Celcuity Inc.7.9M shares45.23%2025-09-302025-11-14 ALKS Alkermes plc8.1M shares26.22%2025-09-302025-11-14 ABCL AbCellera Biologics Inc.27.5M shares0.00%2025-09-302025-11-14 EWTX Edgewise Therapeutics, Inc.7.3M shares0.00%2025-09-302025-11-14 KNSA Kiniksa Pharmaceuticals International, plc2.8M shares0.00%2025-09-302025-11-14 STOK Stoke Therapeutics, Inc.4.6M shares0.00%2025-09-302025-11-14 IMTX Immatics N.V.12.1M shares18.93%2025-09-302025-11-14 GRAL GRAIL, Inc.1.6M shares0.00%2025-09-302025-11-14 IDYA IDEAYA Biosciences, Inc.3.3M shares54.59%2025-09-302025-11-14 IMVT Immunovant, Inc.5.5M shares0.00%2025-09-302025-11-14 IMCR Immunocore Holdings plc2.3M shares0.00%2025-09-302025-11-14 BCYC Bicycle Therapeutics plc10.9M shares0.00%2025-09-302025-11-14 RARE Ultragenyx Pharmaceutical Inc.2.8M shares0.00%2025-09-302025-11-14 ABVX Abivax S.A.875.8K sharesnew addition2025-09-302025-11-14 ARWR Arrowhead Pharmaceuticals, Inc.1.7M shares77.90%2025-09-302025-11-14 ROIV Roivant Sciences Ltd.3.8M shares0.00%2025-09-302025-11-14 DNLI Denali Therapeutics Inc.3.7M shares0.00%2025-09-302025-11-14 MRUS Merus N.V.574.4K shares0.00%2025-09-302025-11-14 NTLA Intellia Therapeutics, Inc.2.7M shares2.65%2025-09-302025-11-14 REPL Replimune Group, Inc.11.0M shares0.00%2025-09-302025-11-14 RAPP Rapport Therapeutics, Inc.1.5M shares181.24%2025-09-302025-11-14 GPCR Structure Therapeutics Inc.1.6M shares-37.97%2025-09-302025-11-14 Celcuity Inc. Celcuity Inc.30.8M sharesnew addition2025-09-302025-11-14 VRDN Viridian Therapeutics, Inc.1.7M shares0.00%2025-09-302025-11-14 IONS Ionis Pharmaceuticals, Inc.566.8K sharesnew addition2025-09-302025-11-14 PRAX Praxis Precision Medicines, Inc.689.5K shares0.00%2025-09-302025-11-14 GLUE Monte Rosa Therapeutics, Inc.4.9M shares0.00%2025-09-302025-11-14 BNTX BioNTech SE368.9K shares0.00%2025-09-302025-11-14 NRIX Nurix Therapeutics, Inc.3.9M shares0.00%2025-09-302025-11-14 DNTH Dianthus Therapeutics, Inc.789.8K shares0.00%2025-09-302025-11-14 TRDA Entrada Therapeutics, Inc.4.9M shares0.00%2025-09-302025-11-14 ARGX argenx SE37.8K shares0.00%2025-09-302025-11-14 RNA Avidity Biosciences, Inc.625.0K sharesnew addition2025-09-302025-11-14 PCVX Vaxcyte, Inc.640.9K shares0.00%2025-09-302025-11-14 IRON Disc Medicine, Inc.337.1K shares0.00%2025-09-302025-11-14 CDTX Cidara Therapeutics, Inc.227.3K shares0.00%2025-09-302025-11-14 CLDX Celldex Therapeutics, Inc.665.4K shares0.00%2025-09-302025-11-14 NGNE Neurogene Inc.991.7K shares0.00%2025-09-302025-11-14 SERA Sera Prognostics, Inc.5.5M shares0.00%2025-09-302025-11-14 SYRE Spyre Therapeutics, Inc.1.0M shares59.57%2025-09-302025-11-14 CERS Cerus Corporation10.0M shares-22.32%2025-09-302025-11-14 AKRO Akero Therapeutics, Inc.324.6K shares0.00%2025-09-302025-11-14 XENE Xenon Pharmaceuticals Inc.370.2K shares0.00%2025-09-302025-11-14 DBVT DBV Technologies S.A.1.5M shares0.00%2025-09-302025-11-14 PRLD Prelude Therapeutics Inc.10.1M shares0.00%2025-09-302025-11-14 ACLX Arcellx, Inc.166.8K shares0.00%2025-09-302025-11-14 CTMX CytomX Therapeutics, Inc.4.3M shares22.00%2025-09-302025-11-14 TSHA Taysha Gene Therapies, Inc.4.0M shares0.00%2025-09-302025-11-14 XNCR Xencor, Inc.1.1M shares64.39%2025-09-302025-11-14 DSGN Design Therapeutics, Inc.1.7M shares0.00%2025-09-302025-11-14 NUVL Nuvalent, Inc.143.9K shares0.00%2025-09-302025-11-14 SION Sionna Therapeutics, Inc.400.0K shares0.00%2025-09-302025-11-14 CRNX Crinetics Pharmaceuticals, Inc.280.0K shares0.00%2025-09-302025-11-14 VKTX Viking Therapeutics, Inc.366.1K sharesnew addition2025-09-302025-11-14 PHVS Pharvaris N.V.375.0K sharesnew addition2025-09-302025-11-14 AGIO Agios Pharmaceuticals, Inc.189.9K shares0.00%2025-09-302025-11-14 SANA Sana Biotechnology, Inc.2.0M shares0.00%2025-09-302025-11-14 SGMT Sagimet Biosciences Inc.953.0K shares0.00%2025-09-302025-11-14 ALMS Alumis Inc.1.6M shares0.00%2025-09-302025-11-14 RLAY Relay Therapeutics, Inc.1.2M shares0.00%2025-09-302025-11-14 SKYE Skye Bioscience, Inc.1.5M shares0.00%2025-09-302025-11-14 HRTX Heron Therapeutics, Inc.4.3M sharesnew addition2025-09-302025-11-14 TCRX TScan Therapeutics, Inc.2.8M shares0.00%2025-09-302025-11-14 MBX MBX Biosciences, Inc.277.8K sharesnew addition2025-09-302025-11-14 VTVT vTv Therapeutics, Inc.148.3K shares52.41%2025-09-302025-11-14 VTYX Ventyx Biosciences, Inc.1.0M sharesnew addition2025-09-302025-11-14 LBRX LB Pharmaceuticals Inc.200.0K sharesnew addition2025-09-302025-11-14 VIR Vir Biotechnology, Inc.542.5K shares0.00%2025-09-302025-11-14 WVE Wave Life Sciences Ltd.344.1K shares0.00%2025-09-302025-11-14 ELVN Enliven Therapeutics, Inc.114.8K shares0.00%2025-09-302025-11-14 TARA Protara Therapeutics, Inc.536.8K shares0.00%2025-09-302025-11-14 TECX Tectonic Therapeutic, Inc.100.0K shares0.00%2025-09-302025-11-14 KALA KALA BIO, Inc.985.1K shares-18.04%2025-09-302025-11-14 GBIO Generation Bio Co.194.5K sharesnew addition2025-09-302025-11-14 CTNM Contineum Therapeutics, Inc.77.7K shares-75.15%2025-09-302025-11-14 ALGS Aligos Therapeutics, Inc.83.1K shares0.00%2025-09-302025-11-14 VYNE VYNE Therapeutics Inc.851.4K sharesnew addition2025-09-302025-11-14 TYRA Tyra Biosciences, Inc.10.6K shares0.00%2025-09-302025-11-14 ACRV Acrivon Therapeutics, Inc.22.8K shares0.00%2025-09-302025-11-14 SRZNW Surrozen, Inc.833.3K shares0.00%2025-09-302025-11-14 OPT Opthea Limited2.1M shares0.00%2025-09-302025-11-14 Call Option Holdings
No call option holdings data available
Put Option Holdings
No put option holdings data available