The Analysis of Siren, L.L.C.'s Holdings
Currently, Siren, L.L.C. holds 115 types of securities in its portfolio with a total value $2.6B. In the most recent quarter, they have increased their positions in RZLT (+4.9M shares, valued at $45.8M), GPCR (+1.0M shares, valued at $28.8M), TNGX (+2.5M shares, valued at $21.2M); decreased their positions in TRVI (-1.4M shares, valued at $12.8M), IRON (-186.0K shares, valued at $12.3M), NAMS (-428.5K shares, valued at $12.2M); initiated new positions in RZLT (+4.9M shares, valued at $45.8M), GPCR (+1.0M shares, valued at $28.8M), QURE (+275.2K shares, valued at $16.1M). Stock Holdings
TickerCompany NameSharesShares âŗ%Event DateReport DateHistory
SRRK Scholar Rock Holding Corp9.3M shares0.00%2025-09-302025-11-13
KYMR Kymera Therapeutics Inc3.4M shares0.00%2025-09-302025-11-13 ONC BeOne Medicines AG493.0K shares-3.33%2025-09-302025-11-13 ARWR Arrowhead Pharmaceuticals Inc2.7M shares0.00%2025-09-302025-11-13 BCAX Bicara Therapeutics Inc5.2M shares0.00%2025-09-302025-11-13 CNTA Centessa Pharmaceuticals PLC3.2M shares-6.72%2025-09-302025-11-13 CRNX Crinetics Pharmaceuticals Inc1.7M shares0.00%2025-09-302025-11-13 EWTX Edgewise Therapeutics Inc3.9M shares23.31%2025-09-302025-11-13 IRON Disc Medicine Inc913.4K shares-16.92%2025-09-302025-11-13 DYN Dyne Therapeutics Inc4.7M shares-2.22%2025-09-302025-11-13 APLS Apellis Pharmaceuticals Inc2.6M shares0.00%2025-09-302025-11-13 RNA Avidity Biosciences Inc1.3M shares15.76%2025-09-302025-11-13 STOK Stoke Therapeutics Inc2.2M shares0.00%2025-09-302025-11-13 LXRX Lexicon Pharmaceuticals Inc38.9M shares0.00%2025-09-302025-11-13 RYTM Rhythm Pharmaceuticals Inc500.0K shares22.02%2025-09-302025-11-13 TNGX Tango Therapeutics Inc5.9M shares74.84%2025-09-302025-11-13 RVMD Revolution Medicines Inc1.0M shares11.18%2025-09-302025-11-13 ASND Ascendis Pharma A/S235.9K shares-4.10%2025-09-302025-11-13 RZLT Rezolute Inc4.9M sharesnew addition2025-09-302025-11-13 SLDB Solid Biosciences Inc7.4M shares0.00%2025-09-302025-11-13 SEPN Septerna Inc2.2M shares0.00%2025-09-302025-11-13 RCUS Arcus Biosciences Inc2.9M shares80.64%2025-09-302025-11-13 TSHA Taysha Gene Therapies Inc11.0M shares0.00%2025-09-302025-11-13 TBLA Taboola.com Ltd10.0M shares0.00%2025-09-302025-11-13 XENE Xenon Pharmaceuticals Inc812.8K shares0.00%2025-09-302025-11-13 SLNO Soleno Therapeutics Inc467.3K shares0.00%2025-09-302025-11-13 RAPP Rapport Therapeutics Inc1.1M shares178.35%2025-09-302025-11-13 GPCR Structure Therapeutics Inc1.0M sharesnew addition2025-09-302025-11-13 WVE WAVE Life Sciences Ltd3.7M shares0.00%2025-09-302025-11-13 RELY Remitly Global Inc1.6M shares213.95%2025-09-302025-11-13 COGT Cogent Biosciences Inc1.7M shares101.82%2025-09-302025-11-13 TRVI Trevi Therapeutics Inc2.5M shares-35.59%2025-09-302025-11-13 NAMS NewAmsterdam Pharma Company NV765.7K shares-35.88%2025-09-302025-11-13 KRRO Korro Bio Inc418.8K shares0.00%2025-09-302025-11-13 ERAS Erasca Inc8.8M shares0.00%2025-09-302025-11-13 IHS IHS Holding Limited2.4M shares0.00%2025-09-302025-11-13 QURE Uniqure NV275.2K sharesnew addition2025-09-302025-11-13 BCYC Bicycle Therapeutics PLC2.0M shares0.00%2025-09-302025-11-13 SLN Silence Therapeutics PLC2.9M shares0.00%2025-09-302025-11-13 RAPT RAPT Therapeutics Inc580.5K sharesnew addition2025-09-302025-11-13 UPB Upstream Bio Inc788.5K shares0.00%2025-09-302025-11-13 GOSS Gossamer Bio Inc5.2M shares0.00%2025-09-302025-11-13 AVBP Arrivent Biopharma Inc700.0K shares0.00%2025-09-302025-11-13 AMZN Amazon.com Inc58.5K shares3.54%2025-09-302025-11-13 ORIC Oric Pharmaceuticals Inc1.0M shares0.00%2025-09-302025-11-13 DNLI Denali Therapeutics Inc821.5K shares0.00%2025-09-302025-11-13 IONQ IONQ Inc170.0K shares0.00%2025-09-302025-11-13 SION Sionna Therapeutics Inc325.0K shares0.00%2025-09-302025-11-13 CRWD CrowdStrike Holdings Inc18.5K shares0.00%2025-09-302025-11-13 MSFT Microsoft Corp17.1K shares6.19%2025-09-302025-11-13 SEER Seer Inc4.0M shares0.00%2025-09-302025-11-13 NBIS Nebius Group NV72.6K shares42.35%2025-09-302025-11-13 NMRA Neumora Therapeutics Inc4.4M shares0.00%2025-09-302025-11-13 TSM Taiwan Semiconductor Manufacturing Co Ltd28.2K shares-7.54%2025-09-302025-11-13 CRM Salesforce Inc30.1K shares33.19%2025-09-302025-11-13 CGEM Cullinan Therapeutics Inc1.2M shares0.00%2025-09-302025-11-13 NVDA NVIDIA Corp37.5K shares-25.01%2025-09-302025-11-13 NOW ServiceNow Inc7.1K shares39.02%2025-09-302025-11-13 SYRE Spyre Therapeutics Inc368.6K shares0.00%2025-09-302025-11-13 RNAC Cartesian Therapeutics Inc563.3K shares0.00%2025-09-302025-11-13 PDD PDD Holdings Inc43.4K shares-17.96%2025-09-302025-11-13 ELDN Eledon Pharmaceuticals Inc2.1M shares200.33%2025-09-302025-11-13 ADBE Adobe Inc15.1K shares0.00%2025-09-302025-11-13 GOOGL Alphabet Inc21.2K shares-58.18%2025-09-302025-11-13 FROG Jfrog Ltd107.1K shares0.00%2025-09-302025-11-13 SGMT Sagimet Biosciences Inc724.8K shares0.00%2025-09-302025-11-13 DT Dynatrace Inc100.2K shares33.23%2025-09-302025-11-13 DDOG Datadog Inc32.9K shares-14.31%2025-09-302025-11-13 NBP I-Mab1.2M sharesnew addition2025-09-302025-11-13 AGEN Agenus Inc1.1M shares0.00%2025-09-302025-11-13 LXEO Lexeo Therapeutics Inc603.4K shares0.00%2025-09-302025-11-13 BDTX Black Diamond Therapeutics Inc1.0M shares0.00%2025-09-302025-11-13 WHWK Whitehawk Therapeutics Inc2.1M shares0.00%2025-09-302025-11-13 VTVT vTv Therapeutics Inc163.0K sharesnew addition2025-09-302025-11-13 TIL Instil Bio Inc203.9K shares0.00%2025-09-302025-11-13 FHTX Foghorn Therapeutics Inc720.7K shares0.00%2025-09-302025-11-13 PRQR ProQR Therapeutics NV1.6M shares0.00%2025-09-302025-11-13 EDU New Oriental Education & Technology Group Inc62.0K shares-13.89%2025-09-302025-11-13 CRWV CoreWeave Inc24.0K sharesnew addition2025-09-302025-11-13 PEPG PepGen Inc700.0K sharesnew addition2025-09-302025-11-13 GTLB GitLab Inc64.0K shares82.86%2025-09-302025-11-13 BEKE Ke Holdings Inc145.0K shares38.10%2025-09-302025-11-13 PANW Palo Alto Networks Inc13.4K shares16.96%2025-09-302025-11-13 TENX Tenax Therapeutics Inc352.4K sharesnew addition2025-09-302025-11-13 WK Workiva Inc30.0K shares7.14%2025-09-302025-11-13 QCOM Qualcomm Inc14.0K shares0.00%2025-09-302025-11-13 BIOA BIOAGE Labs Inc382.4K shares0.00%2025-09-302025-11-13 KDP Keurig Dr Pepper Inc77.0K sharesnew addition2025-09-302025-11-13 HUBS HubSpot Inc4.0K shares33.33%2025-09-302025-11-13 CMG Chipotle Mexican Grill Inc47.5K sharesnew addition2025-09-302025-11-13 KLRS Kalaris Therapeutics Inc318.3K shares12.63%2025-09-302025-11-13 GBIO Generation Bio Co296.9K sharesnew addition2025-09-302025-11-13 CLBT Cellebrite DI Ltd90.0K shares50.00%2025-09-302025-11-13 PRMB Primo Brands Corp75.0K shares100.00%2025-09-302025-11-13 SPOT Spotify Technology SA2.2K sharesnew addition2025-09-302025-11-13 NIQ NIQ Global Intelligence PLC95.0K sharesnew addition2025-09-302025-11-13 MNDY monday.com Ltd7.0K sharesnew addition2025-09-302025-11-13 SAIL SailPoint Inc50.0K shares0.00%2025-09-302025-11-13 ESTC Elastic NV12.5K sharesnew addition2025-09-302025-11-13 IREN IREN Ltd20.0K sharesnew addition2025-09-302025-11-13 SEMR SEMrush Holdings Inc125.0K shares0.00%2025-09-302025-11-13 AS Amer Sports Inc25.0K sharesnew addition2025-09-302025-11-13 PINS Pinterest Inc25.0K sharesnew addition2025-09-302025-11-13 FIG Figma Inc15.0K sharesnew addition2025-09-302025-11-13 CFLT Confluent Inc37.5K sharesnew addition2025-09-302025-11-13 PCOR Procore Technologies Inc10.0K shares0.00%2025-09-302025-11-13 ALAB Astera Labs Inc3.5K sharesnew addition2025-09-302025-11-13 TSLA Tesla Inc1.5K shares-62.50%2025-09-302025-11-13 CHYM Chime Financial Inc25.0K sharesnew addition2025-09-302025-11-13 CCC CCC Intelligent Solutions Holdings Inc50.0K shares0.00%2025-09-302025-11-13 KVUE Kenvue Inc25.0K sharesnew addition2025-09-302025-11-13 VRT Vertiv Holdings Co2.0K shares0.00%2025-09-302025-11-13 CYCN Cyclerion Therapeutics Inc116.2K shares0.00%2025-09-302025-11-13 CRBU Caribou Biosciences Inc105.3K shares0.00%2025-09-302025-11-13 IRWD Ironwood Pharmaceuticals Inc110.5K shares0.00%2025-09-302025-11-13 Call Option Holdings
No call option holdings data available
Put Option Holdings
No put option holdings data available