The Analysis of Siren, L.L.C.'s Holdings
Currently, Siren, L.L.C. holds 113 types of securities in its portfolio with a total value $3.4B. In the most recent quarter, they have increased their positions in OLMA (+3.3M shares, valued at $82.5M), SRRK (+1.6M shares, valued at $69.4M), N/A (+1.7M shares, valued at $44.2M); decreased their positions in N/A (-1.2M shares, valued at $77.6M), DYN (-1.2M shares, valued at $24.0M), WVE (-1.2M shares, valued at $21.2M); initiated new positions in OLMA (+3.3M shares, valued at $82.5M), N/A (+1.7M shares, valued at $44.2M), N/A (+1.9M shares, valued at $35.6M). Stock Holdings
TickerCompany NameSharesShares âŗ%Event DateReport DateHistory
SRRK Scholar Rock Holding Corp10.8M shares17.03%2025-12-312026-02-13
KYMR Kymera Therapeutics Inc3.3M shares-4.12%2025-12-312026-02-13 ONC BeOne Medicines AG500.0K shares1.42%2025-12-312026-02-13 EWTX Edgewise Therapeutics Inc4.5M shares16.24%2025-12-312026-02-13 RVMD Revolution Medicines Inc1.3M shares27.92%2025-12-312026-02-13 CNTA Centessa Pharmaceuticals PLC4.0M shares24.79%2025-12-312026-02-13 BCAX Bicara Therapeutics Inc5.2M shares0.00%2025-12-312026-02-13 OLMA Olema Pharmaceuticals Inc3.3M sharesnew addition2025-12-312026-02-13 IRON Disc Medicine Inc988.4K shares8.21%2025-12-312026-02-13 GPCR Structure Therapeutics Inc1.1M shares5.05%2025-12-312026-02-13 TNGX Tango Therapeutics Inc8.2M shares38.79%2025-12-312026-02-13 RCUS Arcus Biosciences Inc3.0M shares3.26%2025-12-312026-02-13 STOK Stoke Therapeutics Inc2.2M shares0.00%2025-12-312026-02-13 CRNX Crinetics Pharmaceuticals Inc1.5M shares-10.72%2025-12-312026-02-13 DYN Dyne Therapeutics Inc3.5M shares-25.93%2025-12-312026-02-13 APLS Apellis Pharmaceuticals Inc2.6M shares0.00%2025-12-312026-02-13 COGT Cogent Biosciences Inc1.6M shares-5.51%2025-12-312026-02-13 SEPN Septerna Inc2.0M shares-9.19%2025-12-312026-02-13 TSHA Taysha Gene Therapies Inc10.1M shares-8.03%2025-12-312026-02-13 RYTM Rhythm Pharmaceuticals Inc500.0K shares0.00%2025-12-312026-02-13 ASND Ascendis Pharma A/S235.9K shares0.00%2025-12-312026-02-13 TBLA Taboola.com Ltd10.0M shares0.00%2025-12-312026-02-13 LXRX Lexicon Pharmaceuticals Inc38.9M shares0.00%2025-12-312026-02-13 Zymeworks Inc Zymeworks Inc1.7M sharesnew addition2025-12-312026-02-13 WVE WAVE Life Sciences Ltd2.5M shares-33.72%2025-12-312026-02-13 XENE Xenon Pharmaceuticals Inc812.8K shares0.00%2025-12-312026-02-13 ERAS Erasca Inc8.8M shares0.00%2025-12-312026-02-13 TRVI Trevi Therapeutics Inc2.3M shares-9.85%2025-12-312026-02-13 SYRE Spyre Therapeutics Inc818.6K shares122.08%2025-12-312026-02-13 MLYS Mineralys Therapeutics Inc700.0K sharesnew addition2025-12-312026-02-13 DNLI Denali Therapeutics Inc1.4M shares69.99%2025-12-312026-02-13 RELY Remitly Global Inc1.6M shares0.00%2025-12-312026-02-13 FULC Fulcrum Therapeutics Inc1.9M sharesnew addition2025-12-312026-02-13 RAPP Rapport Therapeutics Inc708.5K shares-32.75%2025-12-312026-02-13 SLN Silence Therapeutics PLC2.9M shares0.00%2025-12-312026-02-13 IHS IHS Holding Limited2.4M shares0.00%2025-12-312026-02-13 GOSS Gossamer Bio Inc5.2M shares0.00%2025-12-312026-02-13 UPB Upstream Bio Inc588.5K shares-25.37%2025-12-312026-02-13 BCYC Bicycle Therapeutics PLC2.0M shares0.00%2025-12-312026-02-13 CGEM Cullinan Therapeutics Inc1.2M shares0.00%2025-12-312026-02-13 SION Sionna Therapeutics Inc300.0K shares-7.69%2025-12-312026-02-13 NBP NovaBridge Biosciences3.0M shares157.30%2025-12-312026-02-13 AMZN Amazon.com Inc51.5K shares-11.97%2025-12-312026-02-13 NMRA Neumora Therapeutics Inc6.3M shares44.29%2025-12-312026-02-13 IVVD Invivyd Inc4.0M sharesnew addition2025-12-312026-02-13 TSM Taiwan Semiconductor Manufacturing Co Ltd27.7K shares-1.77%2025-12-312026-02-13 ORIC Oric Pharmaceuticals Inc1.0M shares0.00%2025-12-312026-02-13 PVLA Palvella Therapeutics Inc75.0K sharesnew addition2025-12-312026-02-13 CRWD CrowdStrike Holdings Inc16.5K shares-10.81%2025-12-312026-02-13 IONQ IONQ Inc170.0K shares0.00%2025-12-312026-02-13 SEER Seer Inc4.0M shares0.00%2025-12-312026-02-13 MSFT Microsoft Corp15.0K shares-12.54%2025-12-312026-02-13 PDD PDD Holdings Inc63.4K shares46.08%2025-12-312026-02-13 LXEO Lexeo Therapeutics Inc720.6K shares19.42%2025-12-312026-02-13 NVDA NVIDIA Corp37.5K shares0.00%2025-12-312026-02-13 CRM Salesforce Inc26.1K shares-13.29%2025-12-312026-02-13 CMPS Compass Pathways PLC1.0M sharesnew addition2025-12-312026-02-13 WK Workiva Inc79.1K shares163.74%2025-12-312026-02-13 ZURA Zura Bio Ltd1.3M sharesnew addition2025-12-312026-02-13 Alphabet Inc Alphabet Inc20.7K shares-2.36%2025-12-312026-02-13 NBIS Nebius Group NV76.2K shares4.98%2025-12-312026-02-13 SVRA Savara Inc1.0M sharesnew addition2025-12-312026-02-13 XFOR X4 Pharmaceuticals Inc1.5M sharesnew addition2025-12-312026-02-13 FROG Jfrog Ltd93.6K shares-12.60%2025-12-312026-02-13 NOW ServiceNow Inc35.6K shares400.00%2025-12-312026-02-13 WHWK Whitehawk Therapeutics Inc2.1M shares0.00%2025-12-312026-02-13 DT Dynatrace Inc115.2K shares14.97%2025-12-312026-02-13 DDOG Datadog Inc36.4K shares10.63%2025-12-312026-02-13 ALMS Alumis Inc500.0K sharesnew addition2025-12-312026-02-13 META Meta Platforms Inc7.2K sharesnew addition2025-12-312026-02-13 PEPG PepGen Inc700.0K shares0.00%2025-12-312026-02-13 SGMT Sagimet Biosciences Inc724.8K shares0.00%2025-12-312026-02-13 ADBE Adobe Inc12.1K shares-19.93%2025-12-312026-02-13 FHTX Foghorn Therapeutics Inc720.7K shares0.00%2025-12-312026-02-13 GTLB GitLab Inc99.0K shares54.69%2025-12-312026-02-13 KLRS Kalaris Therapeutics Inc435.8K shares36.93%2025-12-312026-02-13 EDU New Oriental Education & Technology Group Inc62.0K shares0.00%2025-12-312026-02-13 AGEN Agenus Inc1.1M shares0.00%2025-12-312026-02-13 Medline Inc Medline Inc75.0K sharesnew addition2025-12-312026-02-13 KRRO Korro Bio Inc347.7K shares-16.98%2025-12-312026-02-13 CLBT Cellebrite DI Ltd150.0K shares66.67%2025-12-312026-02-13 RANI Rani Therapeutics Holdings Inc2.0M sharesnew addition2025-12-312026-02-13 ZS Zscaler Inc12.0K sharesnew addition2025-12-312026-02-13 BDTX Black Diamond Therapeutics Inc1.0M shares0.00%2025-12-312026-02-13 MNDY monday.com Ltd17.0K shares142.86%2025-12-312026-02-13 Broadcom Inc Broadcom Inc7.0K sharesnew addition2025-12-312026-02-13 QCOM Qualcomm Inc14.0K shares0.00%2025-12-312026-02-13 ARM Arm Holdings PLC21.5K sharesnew addition2025-12-312026-02-13 BEKE Ke Holdings Inc145.0K shares0.00%2025-12-312026-02-13 PANW Palo Alto Networks Inc11.4K shares-14.87%2025-12-312026-02-13 CRWV CoreWeave Inc27.5K shares14.58%2025-12-312026-02-13 IREN IREN Ltd43.1K shares115.50%2025-12-312026-02-13 VRNS Varonis Systems Inc37.5K sharesnew addition2025-12-312026-02-13 PRMB Primo Brands Corp75.0K shares0.00%2025-12-312026-02-13 GBIO Generation Bio Inc201.4K shares-32.16%2025-12-312026-02-13 FIG Figma Inc25.0K shares66.67%2025-12-312026-02-13 TSLA Tesla Inc1.5K shares0.00%2025-12-312026-02-13 CRBU Caribou Biosciences Inc105.3K shares0.00%2025-12-312026-02-13 Call Option Holdings
No call option holdings data available
Put Option Holdings
No put option holdings data available