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The Analysis of Paradigm Biocapital Advisors LP's Holdings & P&L

Currently, Paradigm Biocapital Advisors LP holds 36 types of securities in its portfolio with a total value $4.9B. In the most recent quarter, they have increased their positions in ACLX (+5.8M shares, valued at $663.0M), RVMD (+6.7M shares, valued at $647.3M), NUVL (+5.3M shares, valued at $545.5M); decreased their positions in ACHV (-9.0M shares, valued at $37.5M); initiated new positions in ACLX (+5.8M shares, valued at $663.0M), RVMD (+6.7M shares, valued at $647.3M), NUVL (+5.3M shares, valued at $545.5M).

1M P&L

+111.2M+2.59%

3M P&L

+253.2M+6.11%

HY P&L

+664.6M+17.79%

P&L figures are estimated based on reported 13F stock holdings and market price changes. They are approximations and may not reflect actual fund performance. Stock split events may also affect the accuracy of these calculations, and we cannot guarantee that all splits have been fully accounted for.

Top Holding Treemap

Top Industries by Value

1Biotechnology4.9B

100.0%

Top Industries by Stock Count

1Biotechnology33 stocks

100.0%

Sponsored

Stock Holdings

TickerCompany NameSharesShares △%Event DateReport DateHistory

ACLX ARCELLX INC5.8M sharesnew addition2026-03-312026-05-15

RVMD REVOLUTION MEDICINES INC6.7M sharesnew addition2026-03-312026-05-15

NUVL NUVALENT INC5.3M sharesnew addition2026-03-312026-05-15

PCVX VAXCYTE INC4.8M sharesnew addition2026-03-312026-05-15

EWTX EDGEWISE THERAPEUTICS INC7.4M sharesnew addition2026-03-312026-05-15

GMAB GENMAB A/S8.0M sharesnew addition2026-03-312026-05-15

INSM INSMED INC1.3M sharesnew addition2026-03-312026-05-15

TARS TARSUS PHARMACEUTICALS INC2.6M sharesnew addition2026-03-312026-05-15

Sponsored

BLTE BELITE BIO INC1.1M sharesnew addition2026-03-312026-05-15

ERAS ERASCA INC10.4M sharesnew addition2026-03-312026-05-15

CNTA CENTESSA PHARMACEUTICALS PLC3.6M sharesnew addition2026-03-312026-05-15

OLMA OLEMA PHARMACEUTICALS INC8.0M sharesnew addition2026-03-312026-05-15

TERN TERNS PHARMACEUTICALS INC2.2M sharesnew addition2026-03-312026-05-15

ORKA ORUKA THERAPEUTICS INC2.3M sharesnew addition2026-03-312026-05-15

APGE APOGEE THERAPEUTICS INC1.3M sharesnew addition2026-03-312026-05-15

SYRE SPYRE THERAPEUTICS INC2.0M sharesnew addition2026-03-312026-05-15

Sponsored

CYTK CYTOKINETICS INC1.5M sharesnew addition2026-03-312026-05-15

ABVX ABIVAX SA772.5K sharesnew addition2026-03-312026-05-15

TNGX TANGO THERAPEUTICS INC4.0M sharesnew addition2026-03-312026-05-15

MAZE MAZE THERAPEUTICS INC2.7M sharesnew addition2026-03-312026-05-15

TYRA TYRA BIOSCIENCES INC2.1M sharesnew addition2026-03-312026-05-15

VRDN VIRIDIAN THERAPEUTICS INC3.1M sharesnew addition2026-03-312026-05-15

SRRK SCHOLAR ROCK HLDG CORP1.2M sharesnew addition2026-03-312026-05-15

MIRM MIRUM PHARMACEUTICALS INC625.0K sharesnew addition2026-03-312026-05-15

Sponsored

EYPT EYEPOINT INC3.1M sharesnew addition2026-03-312026-05-15

LXEO LEXEO THERAPEUTICS INC6.2M sharesnew addition2026-03-312026-05-15

VERADERMICS INC VERADERMICS INC525.0K sharesnew addition2026-03-312026-05-15

VOR VOR BIOPHARMA INC1.8M sharesnew addition2026-03-312026-05-15

URGN UROGEN PHARMA LTD1.7M sharesnew addition2026-03-312026-05-15

GPCR STRUCTURE THERAPEUTICS INC545.3K sharesnew addition2026-03-312026-05-15

ACHV 865.3K shares-91.26%2026-05-042026-05-11

IVA INVENTIVA SA4.0M sharesnew addition2026-03-312026-05-15

Sponsored

ORIC ORIC PHARMACEUTICALS INC1.7M sharesnew addition2026-03-312026-05-15

ASSEMBLY BIOSCIENCES INC ASSEMBLY BIOSCIENCES INC665.3K sharesnew addition2026-03-312026-05-15

BRIDGEBIO ONCOLOGY THERAPEUT BRIDGEBIO ONCOLOGY THERAPEUT868.2K sharesnew addition2026-03-312026-05-15

KLRS KALARIS THERAPEUTICS INC700.0K sharesnew addition2026-03-312026-05-15

ACLX

ARCELLX INC

New

Shares5.8M

Event2026-03-31

Filed2026-05-15

RVMD

REVOLUTION MEDICINES INC

New

Shares6.7M

Event2026-03-31

Filed2026-05-15

NUVL

NUVALENT INC

New

Shares5.3M

Event2026-03-31

Filed2026-05-15

PCVX

VAXCYTE INC

New

Shares4.8M

Event2026-03-31

Filed2026-05-15

EWTX

EDGEWISE THERAPEUTICS INC

New

Shares7.4M

Event2026-03-31

Filed2026-05-15

GMAB

GENMAB A/S

New

Shares8.0M

Event2026-03-31

Filed2026-05-15

INSM

INSMED INC

New

Shares1.3M

Event2026-03-31

Filed2026-05-15

TARS

TARSUS PHARMACEUTICALS INC

New

Shares2.6M

Event2026-03-31

Filed2026-05-15

BLTE

BELITE BIO INC

New

Shares1.1M

Event2026-03-31

Filed2026-05-15

ERAS

ERASCA INC

New

Shares10.4M

Event2026-03-31

Filed2026-05-15

CNTA

CENTESSA PHARMACEUTICALS PLC

New

Shares3.6M

Event2026-03-31

Filed2026-05-15

OLMA

OLEMA PHARMACEUTICALS INC

New

Shares8.0M

Event2026-03-31

Filed2026-05-15

TERN

TERNS PHARMACEUTICALS INC

New

Shares2.2M

Event2026-03-31

Filed2026-05-15

ORKA

ORUKA THERAPEUTICS INC

New

Shares2.3M

Event2026-03-31

Filed2026-05-15

APGE

APOGEE THERAPEUTICS INC

New

Shares1.3M

Event2026-03-31

Filed2026-05-15

SYRE

SPYRE THERAPEUTICS INC

New

Shares2.0M

Event2026-03-31

Filed2026-05-15

CYTK

CYTOKINETICS INC

New

Shares1.5M

Event2026-03-31

Filed2026-05-15

ABVX

ABIVAX SA

New

Shares772.5K

Event2026-03-31

Filed2026-05-15

TNGX

TANGO THERAPEUTICS INC

New

Shares4.0M

Event2026-03-31

Filed2026-05-15

MAZE

MAZE THERAPEUTICS INC

New

Shares2.7M

Event2026-03-31

Filed2026-05-15

TYRA

TYRA BIOSCIENCES INC

New

Shares2.1M

Event2026-03-31

Filed2026-05-15

VRDN

VIRIDIAN THERAPEUTICS INC

New

Shares3.1M

Event2026-03-31

Filed2026-05-15

SRRK

SCHOLAR ROCK HLDG CORP

New

Shares1.2M

Event2026-03-31

Filed2026-05-15

MIRM

MIRUM PHARMACEUTICALS INC

New

Shares625.0K

Event2026-03-31

Filed2026-05-15

EYPT

EYEPOINT INC

New

Shares3.1M

Event2026-03-31

Filed2026-05-15

LXEO

LEXEO THERAPEUTICS INC

New

Shares6.2M

Event2026-03-31

Filed2026-05-15

VERADERMICS INC

New

Shares525.0K

Event2026-03-31

Filed2026-05-15

VOR

VOR BIOPHARMA INC

New

Shares1.8M

Event2026-03-31

Filed2026-05-15

URGN

UROGEN PHARMA LTD

New

Shares1.7M

Event2026-03-31

Filed2026-05-15

GPCR

STRUCTURE THERAPEUTICS INC

New

Shares545.3K

Event2026-03-31

Filed2026-05-15

ACHV

-91.26%

Shares865.3K

Event2026-05-04

Filed2026-05-11

IVA

INVENTIVA SA

New

Shares4.0M

Event2026-03-31

Filed2026-05-15

ORIC

ORIC PHARMACEUTICALS INC

New

Shares1.7M

Event2026-03-31

Filed2026-05-15

ASSEMBLY BIOSCIENCES INC

New

Shares665.3K

Event2026-03-31

Filed2026-05-15

BRIDGEBIO ONCOLOGY THERAPEUT

New

Shares868.2K

Event2026-03-31

Filed2026-05-15

KLRS

KALARIS THERAPEUTICS INC

New

Shares700.0K

Event2026-03-31

Filed2026-05-15

Call Option Holdings

No call option holdings data available

Put Option Holdings

No put option holdings data available