Vanguard Group Inc Increases Stake in Rhythm Pharmaceuticals Inc

The Vanguard Group Inc has filed a Schedule 13G/A amendment, disclosing its increased ownership in Rhythm Pharmaceuticals Inc. As of September 30, 2025, Vanguard holds 4,996,427 shares, representing 7.52% of the company's common stock. The filing indicates that Vanguard has sole dispositive power over 4,529,636 shares and shared dispositive power over 466,791 shares. The shares are held on behalf of Vanguard's clients, including investment companies and managed accounts, with no single client owning more than 5% of the securities. The filing was signed by Ashley Grim, Head of Global Fund Administration, on October 30, 2025.