Amendment No. 8 to Schedule 13D for VOR Biopharma Inc.

This filing is Amendment No. 8 to Schedule 13D/A by RA Capital Management, L.P. regarding its holdings in VOR Biopharma Inc. The amendment updates the ownership details and transactions involving the common stock of VOR Biopharma Inc. RA Capital Management, L.P., along with Peter Kolchinsky and Rajeev Shah, collectively referred to as the Reporting Persons, report beneficial ownership of 1,186,500 shares, representing 17.3% of the outstanding common stock. The filing details recent transactions, including open market sales of shares by the Fund on October 21, 23, 24, and 27, 2025, at weighted average prices ranging from $28.00 to $28.475. The Reporting Persons disclaim beneficial ownership of the securities except for the purpose of determining their obligations under Section 13(d) of the Securities Exchange Act of 1934.