Amendment to Schedule 13D Filing for Celcuity Inc.

Baker Bros. Advisors LP and its affiliates (Reporting Persons) have filed an Amendment No. 1 to Schedule 13D regarding their beneficial ownership of Celcuity Inc. common stock. The amendment supplements previous filings and details changes in ownership limitations. Specifically, on March 20, 2026, the Reporting Persons notified Celcuity Inc. to increase the beneficial ownership limitation from 4.99% to 19.99% concerning prefunded warrants held by two funds, 667 and Baker Brothers Life Sciences, L.P. This increase will become effective on May 20, 2026. The Reporting Persons hold these securities for investment purposes and may adjust their holdings based on various factors, including market conditions and the Issuer's prospects. They may also engage in discussions with the Issuer's management regarding potential business strategies, financing, and further acquisitions or dispositions of securities. As of the filing date, the Reporting Persons may be deemed to beneficially own up to 19.99% of the outstanding common stock. Currently, due to ownership limitations, they cannot convert their 2.75% Convertible Notes.