Power of Attorney for Raymond J. Deshaies

The document is a Power of Attorney executed by Raymond J. Deshaies, a director of Xencor, Inc. It appoints Bassil I. Dahiyat, Bart J. Cornelissen, and Celia Eckert as attorneys-in-fact to act on his behalf in matters related to SEC filings. Specifically, they are authorized to execute and file Forms 3, 4, and 5 in accordance with Section 16(a) of the Securities Exchange Act of 1934. The attorneys-in-fact are also empowered to perform any necessary actions to complete and file these forms, including amendments, and to take any other actions deemed beneficial or legally required. The Power of Attorney remains in effect until Deshaies is no longer required to file these forms, he revokes it in writing, or the attorneys-in-fact are no longer employed by Xencor, Inc.