SEC Filing Form 4 for Jose Manuel Otero

Jose Manuel Otero, Chief Operating Officer of Lexeo Therapeutics, Inc., acquired 2,110 shares of common stock on September 14, 2026, for $2.644 per share, bringing his total shares to 138,288. This acquisition was made under the Lexeo Therapeutics, Inc. 2023 Employee Stock Purchase Plan and is exempt under Rule 16b-3(c) and Rule 16b-3(d). Additionally, on September 24, 2026, Otero was granted a stock option to acquire 54,750 shares of common stock at an exercise price of $3.39 per share. The option vests 25% on September 24, 2027, with the remainder vesting monthly over the following year, contingent upon continued service. Otero