Form 4 Filing for Joseph K. Schachle

This filing reports a transaction by Joseph K. Schachle, Chief Operating Officer of Opus Genetics, Inc. On April 23, 2026, Mr. Schachle sold 4,697 shares of Common Stock at a price of $5.2202 per share. This sale was an automatic transaction to cover tax withholding obligations arising from a restricted stock units award and does not represent a discretionary trade. Following this transaction, Mr. Schachle directly owns 296,084 shares of Common Stock.