Form 4 Filing by Benjamin R. Yerxa

This filing details a transaction by Benjamin R. Yerxa, President of Opus Genetics, Inc. On April 23, 2026, Mr. Yerxa sold 7,470 shares of Common Stock at a weighted average price of $5.2371 per share, with transactions ranging from $5.2314 to $5.2413. This sale was conducted automatically to cover tax obligations arising from a restricted stock unit award vesting and settlement, and does not represent a discretionary trade. Following the transaction, Mr. Yerxa holds 711,535 shares of Common Stock directly.