Form 4 Filing for Roberto Mignone

This filing details transactions made by Roberto Mignone, a director at Guardant Health, Inc. On May 21, 2026, and June 21, 2026, Mignone acquired 264 shares of Common Stock in two separate transactions, bringing his total holdings to 9218 and 9482 shares respectively. Concurrently, Mignone disposed of 264 Restricted Stock Units (RSUs) on both dates, reducing his RSU holdings to 7656 and 7392 shares. The RSUs are tied to Guardant Health, Inc. Common Stock. The RSUs granted on November 8, 2024, vest over a four-year period, with 25% vesting on October 21, 2025, and the remaining 75% vesting monthly thereafter.