Denali Therapeutics Inc. - Form 4 Filing for Carole Ho

On August 5, 2025, Carole Ho, the Chief Medical Officer of Denali Therapeutics Inc., filed a Form 4 with the SEC. The filing details transactions involving the company's common stock and stock options. Ho acquired 44,655 shares of common stock at a price of $0.68 per share, increasing her total holdings to 220,328 shares, including 134,030 unvested RSUs. Additionally, Ho exercised stock options to buy 44,655 shares at $0.68 per share, with 50% of the shares vesting on March 3, 2021, and the remaining 50% vesting upon the company's stock price reaching $80.00 per share for 90 consecutive trading days. Ho also indirectly holds 183,219 shares through the Rohatgi-Ho Family 2009 Revocable Trust and 25,000 shares through The Rohatgi-Ho Irrevocable GST Trust for her children.