Form 4 Filing for Derek J. Maetzold

Derek J. Maetzold, Pres. & Chief Exec. Officer of CASTLE BIOSCIENCES INC, reported the sale of 14,496 shares of Common Stock on October 19, 2026. The transactions were conducted under a Rule 10b5-1 plan. A total of 8,580 shares were sold directly by Maetzold at a weighted-average price of $31.91, resulting in 12,484 shares remaining. Additionally, 3,198 shares were sold indirectly through The Maetzold Descendants 2020 Trust and 2,718 shares were sold indirectly through the Derek Maetzold 2020 Irrevocable Trust, both at the same weighted-average price. Following these transactions, Maetzold