Insider Transaction Report

This filing details a Form 4 filed by Francois Eric, a director at CERO THERAPEUTICS HOLDINGS, INC. On March 4, 2026, Mr. Eric acquired 1,823,278 stock options with a strike price of $0.055. These options are exercisable and have an expiration date of March 3, 2036. The underlying securities are 1,823,278 shares of Common Stock. The options are subject to vesting conditions, including continuous service through the vesting date or the achievement of a specified clinical milestone in 2026. The filing was signed by Andrew Kucharchuk as Attorney-in-Fact on April 21, 2026.