FMR LLC's Disposal of Beam Therapeutics Inc. Common Stock

FMR LLC, a ten percent owner of Beam Therapeutics Inc., reported the disposal of 459 shares of common stock on October 27, 2025, at a price of $26.68 per share. Following this transaction, FMR LLC's direct ownership was reduced to 14 shares. The filing also disclosed that FMR LLC, through its subsidiaries, holds significant indirect ownership in Beam Therapeutics Inc., including 1,139,443 shares held by F-Prime Capital Partners Healthcare Fund V LP and 841,231 shares held by persons and entities whose shares are subject to reporting by FMR LLC. The filing includes remarks clarifying the ownership structure and control of FMR LLC, particularly the influence of the Johnson family.