Insider Transaction Report for BICYCLE THERAPEUTICS PLC

This report details insider transactions for BICYCLE THERAPEUTICS PLC (BCYC). Jennifer Scott Perry, Chief Operating Officer, reported the sale of 1038 ordinary shares on April 2, 2026, at an average price of $4.91 per share. This sale was to cover tax withholding obligations related to RSU vesting, as mandated by her award agreement and executed through a "sell to cover" transaction. The transaction was made pursuant to a Rule 10b5-1 trading plan. Subsequently, on April 6, 2026, Ms. Perry sold an additional 37 shares at $5.05 per share and 333 shares at an average price of $5.04 per share. These sales also appear to be related to tax withholding obligations, with the latter transaction also conducted under the Rule 10b5-1 trading plan. Following these transactions, Ms. Perry holds 92,464 shares.