Form 4 Filing for Michael Charles Ferguson Hannay

This filing details transactions made by Michael Charles Ferguson Hannay, Chief Production & Supply Chain Officer at BICYCLE THERAPEUTICS PLC. On April 2, 2026, 1521 ordinary shares were disposed of at a weighted average price of $4.91, with individual transactions ranging from $4.88 to $4.98. Following this, 96387 shares were held. On April 6, 2026, an additional 251 ordinary shares were disposed of at $5.05 per share, leaving a total of 96136 shares. The filing notes that the sale of shares on April 2 was to cover statutory tax withholding obligations related to RSU vesting, as mandated by the award agreement, and not a discretionary sale. The exact prices for the April 2nd transactions are available upon request.