Form 4 Filing for BICYCLE THERAPEUTICS PLC

This filing details transactions by Michael Charles Ferguson Hannay, Chief Production and Supply Chain Officer at BICYCLE THERAPEUTICS PLC. On July 2, 2026, 1506 shares of Ordinary Shares were disposed of at a weighted average price of $4.27, with individual transactions ranging from $4.26 to $4.29. Following this, 94630 shares were held. On July 6, 2026, an additional 255 shares were disposed of at a weighted average price of $4.31, with individual transactions ranging from $4.30 to $4.31. This resulted in 94375 shares held post-transaction. Footnote 1 clarifies that these sales were mandated by the Reporting Person's award agreement to cover statutory tax withholding obligations through a "sell to cover" transaction and are not discretionary. The filing is Form 4, indicating a change in beneficial ownership.