Form 4 Filing for BICYCLE THERAPEUTICS PLC

On October 2, 2026, Travis Alvin Thompson, Chief Financial Officer of BICYCLE THERAPEUTICS PLC, reported a sale of 893 ordinary shares. The shares were sold at an average price of $3.47 per share, with individual transactions ranging from $3.41 to $3.525. This sale was mandated to cover statutory tax withholding obligations upon the vesting of RSUs, as per the award agreement, and does not represent a discretionary sale. Following this transaction, Mr. Thompson owns 64,528 shares. On October 5, 2026, Mr. Thompson reported another sale of 79 ordinary shares at an average price of $3.57 per share, with transactions ranging from $3.56 to $3.57. This sale was also to cover tax withholding obligations. After this transaction, Mr. Thompson