Form 4 Filing for Jean-Pierre Bizzari

Jean-Pierre Bizzari, a director at Aprea Therapeutics, Inc., acquired 3,135 shares of Common Stock on June 16, 2026, with a transaction price of $0.00. This acquisition is part of restricted stock units that will vest on June 16, 2027. Additionally, Bizzari was granted 12,555 stock options to buy Common Stock, also vesting on June 16, 2027. Both transactions are subject to continued service and potential acceleration. The filing also notes a post-transaction ownership of 4,180 shares of Common Stock and 12,555 stock options.