Form 4 Filing for Annovis Bio, Inc.

Michael B. Hoffman, a director at Annovis Bio, Inc., reported several transactions on May 20, 2026. He acquired 2,562 shares of Common Stock at $1.75 per share, followed by an acquisition of 18,849 shares at $1.80 per share, and a further acquisition of 54,933 shares at $1.8999 per share. Following these transactions, Mr. Hoffman directly owns 3,364,883 shares. Additionally, he holds 223,357 shares indirectly through The 2024 Hoffman Family Trust, over which he has voting and investment power. The filing was signed by Maria Maccecchini as Attorney-in-Fact on May 21, 2026.