Perceptive Advisors LLC and Joseph Edelman File Schedule 13G for Alto Neuroscience, Inc.

Perceptive Advisors LLC, Joseph Edelman, and Perceptive Life Sciences Master Fund, Ltd. have filed a Schedule 13G with the SEC regarding their ownership of shares in Alto Neuroscience, Inc. The filing indicates that the Reporting Persons collectively own 1,989,393 shares of Common Stock, representing 7.3% of the outstanding shares. The shares are directly held by the Master Fund, with Perceptive Advisors serving as the investment manager and Mr. Edelman as the managing member. The filing certifies that the shares were not acquired for the purpose of influencing the control of the issuer. The event date requiring this filing is October 3, 2025, and the filing was signed on October 10, 2025.