Form 4 Filing for Amylyx Pharmaceuticals, Inc.

This filing details transactions made by Gina Mazzariello, Chief Legal Officer of Amylyx Pharmaceuticals, Inc. On September 10, 2026, Mazzariello sold 9,525 shares of Common Stock at a weighted average price of $32.4556, with individual sales ranging from $32.34 to $33.26. This transaction was to cover tax withholding obligations related to the vesting of performance stock units and was automatic. Additionally, 11 shares of Common Stock were sold at $33.34. Following these transactions, Mazzariello directly owns 190,838 shares of Amylyx Pharmaceuticals, Inc. stock. The filing is Form 4, indicating a change in beneficial ownership.