Officer and Director Stock Transactions

Krishnan Viswanadhan, Chief Strategy and Operations at AGIOS PHARMACEUTICALS, INC., reported transactions on June 18, 2026. Viswanadhan disposed of 3,000 performance share units, which represent a contingent right to receive one share of the issuer's common stock. These units were granted on March 5, 2025, and vesting is subject to achieving specified milestones. The shares related to one such milestone will vest on December 31, 2027. Following this transaction, Viswanadhan holds 9,000 performance share units. Additionally, Viswanadhan acquired 3,000 restricted stock units, each representing a contingent right to receive one share of common stock. Post-transaction, Viswanadhan holds 3,000 restricted stock units. All transactions were direct ownership and had a price of $0.0.