Officer and Director Stock Transactions

Krishnan Viswanadhan, Chief Corp Dev & Strategy at AGIOS PHARMACEUTICALS, INC., reported transactions on April 2, 2026. Viswanadhan acquired 8,100 shares of Common stock through the vesting of performance share units (PSUs), with the PSUs themselves acquired on March 5, 2025. These PSUs vested upon meeting a regulatory milestone. The acquired shares were used to cover a tax withholding obligation, resulting in a sale of 2,959 shares at $34.71 per share. Following these transactions, Viswanadhan directly owns 10,282 shares of common stock.