Form 4 Filing for Agios Pharmaceuticals, Inc.

This filing details transactions by Jeffrey D. Capello, a director at Agios Pharmaceuticals, Inc. On June 18, 2026, Capello acquired 2,816 shares of common stock through the vesting of restricted stock units (RSUs). Additionally, he was granted 2,927 RSUs and 14,950 stock options. The RSUs granted on June 18, 2025, vested on June 18, 2026, with shares to be delivered post-vesting. New RSUs granted on June 18, 2026, will vest on June 18, 2027, and stock options granted on the same date will vest on June 18, 2027. All transactions were reported on a Form 4, with the signature dated June 23, 2026.