Power of Attorney for Roland Kolbeck at Aclaris Therapeutics, Inc.

Roland Kolbeck, Chief Scientific Officer of Aclaris Therapeutics, Inc., has granted a Power of Attorney to Neal Walker, Kevin Balthaser, and Matthew Rothman of the company. This authorization allows them to prepare, execute, and submit Forms 3, 4, and 5 to the Securities and Exchange Commission (SEC) on his behalf, in accordance with Section 16(a) of the Securities Exchange Act of 1934. The Power of Attorney also permits them to perform any necessary acts related to these filings, including filing with the SEC and any stock exchange or self-regulatory association. The Power of Attorney remains in effect until Kolbeck is no longer required to file these forms, he revokes it in writing, or the attorneys-in-fact are no longer employed by the company. The document was executed on July 29, 2025.