Form 4 Filing for Alpha Cognition Inc.

This filing details transactions made by Opaleye Management Inc. concerning Alpha Cognition Inc. (ACOG) stock. On May 20, 2026, Opaleye Management Inc. acquired 8,431 shares at $5.89 per share, increasing their holdings to 2,514,424 shares. This acquisition was made through their managed account, Opaleye, L.P. Subsequently, on May 21, 2026, an additional 15,945 shares were acquired at $5.70 per share, bringing the total shares held to 2,530,369. The filing also notes that Opaleye Management Inc. may be deemed to beneficially own these shares due to its role as investment manager and portfolio manager for the respective entities. Opaleye Management Inc. disclaims beneficial ownership beyond its pecuniary interest.