Insider Transaction Report for Andrew D. Goldberg

This filing details derivative security transactions by Andrew D. Goldberg, CEO and President of ACHIEVE LIFE SCIENCES, INC. On April 18, 2026, Mr. Goldberg acquired 1,800,965 Restricted Stock Units (RSUs), 3,601,929 Stock Options, and 11,706,270 Performance Restricted Stock Units (PRSUs). The RSUs and PRSUs have a transaction price of $0.00, with vesting schedules detailed in footnotes. The stock options also have a transaction price of $0.00 and a conversion/exercise price of $4.25, with vesting occurring in installments starting one year after the transaction date. All these derivative transactions are directly owned by Mr. Goldberg. The report was signed by Sandra Thomson as attorney-in-fact on April 21, 2026.