OrbiMed Entities Sell 104,658 Shares of Adicet Bio Common Stock

This Form 4 filing reports multiple sales of Adicet Bio, Inc. (ACET) common stock by OrbiMed entities between April 7-8, 2026. The transactions involved sales of 104,658 shares across four separate trades at prices ranging from $6.29 to $6.53 per share. The reporting entities include OrbiMed Advisors LLC and seven related OrbiMed investment entities, all acting as ten percent owners. The sales resulted in complete liquidation of positions held through OrbiMed Israel Partners Limited Partnership (29,319 and 2,400 shares sold on April 7, and 32,523 shares sold on April 8) and OrbiMed Israel Partners II, L.P. (40,416 shares sold on April 8). Following these transactions, the OrbiMed entities maintain significant holdings through other investment vehicles totaling 923,286 shares. Carl L. Gordon signed on behalf of all reporting entities.