Nantahala Capital Management Acquires 6% Stake in VYNE Therapeutics Inc.

On May 15, 2026, Nantahala Capital Management, LLC, along with Wilmot B. Harkey and Daniel Mack, filed a Schedule 13G reporting a new 6.00% stake in VYNE Therapeutics Inc. (VYNE). As of the event date on March 31, 2026, the reporting persons collectively beneficially own 2,000,000 shares of common stock. Nantahala Capital Management, a Massachusetts-based investment adviser, manages these shares through various funds and separately managed accounts. Both Mr. Harkey and Mr. Mack are identified as control persons of the firm. The filing indicates that the shares were acquired in the ordinary course of business and not for the purpose of influencing or changing control of the issuer. This position represents a significant increase from zero as of the previous reporting period. The reporting persons share voting and dispositive power over the entire 2,000,000 share block. The principal executive offices of VYNE Therapeutics are located in Stewartsville, New Jersey.