Power of Attorney for Andreas Grauer

This filing details a Power of Attorney granted by Andreas Grauer, Chief Medical Officer of Sagimet Biosciences Inc., to David Happel and Elizabeth Rozek. The attorneys-in-fact are authorized to execute and file various SEC forms, including Forms 3, 4, and 5, Schedule 13D, and Schedule 13G, on behalf of Mr. Grauer. This authorization is necessary for compliance with Section 16(a) of the Securities Exchange Act of 1934. The Power of Attorney remains in effect until Mr. Grauer is no longer required to file these forms or until it is earlier revoked. It also states that the attorneys-in-fact and the Company are not assuming Mr. Grauer's compliance responsibilities, and Mr. Grauer agrees to indemnify them against any claims arising from false information provided.