Form 3 Filing and Power of Attorney for Nathaniel Sisitsky

This filing reports that Nathaniel Sisitsky, Chief Legal Officer of QuidelOrtho Corp, has no securities beneficially owned as of March 23, 2026. Concurrently, a Power of Attorney document, dated March 25, 2026, has been filed. This power of attorney designates Jennifer Ahn, Phillip S. Askim, and Euna Greene as attorneys-in-fact. They are authorized to execute and file all necessary Section 16 forms (Forms 3, 4, and 5) related to the company's securities, including obtaining and managing EDGAR access codes. This authorization remains effective until Sisitsky is no longer required to file such forms or until he revokes it in writing. The attorneys-in-fact and the company acknowledge that the responsibility for Section 16 compliance ultimately rests with Sisitsky.