Ameriprise Financial and Columbia Management Acquire 5.3% Stake in Palisade Bio, Inc.

Ameriprise Financial, Inc. (AFI) and its subsidiary, Columbia Management Investment Advisers, LLC (CMIA), have filed a Schedule 13G regarding their interest in Palisade Bio, Inc. (PALI). As of March 31, 2026, the reporting persons beneficially own 8,711,385 shares of Common Stock, representing a 5.3% ownership stake in the company. This filing marks an increase from a previous ownership position of 0.0%, indicating a new significant holding. CMIA, an investment adviser, is the primary entity through which the shares are held, while AFI is the parent holding company. Both entities reported shared voting and dispositive power over the total share count. The filing was made under Rule 13d-1(b), certifying that the securities were acquired in the ordinary course of business and not for the purpose of influencing or changing the control of the issuer. The principal executive offices for Palisade Bio are located in Denver, Colorado, and the reporting persons are based in Minneapolis and Boston.