Form 4 Filing for G. Jan Van Heek - Stock Option Grant

This filing details a Form 4 submission by G. Jan Van Heek, a director at Minerva Neurosciences, Inc. (NERV). On December 22, 2025, Van Heek was granted a stock option to purchase 50,000 shares of Common Stock at a price of $3.98 per share. The option vests in four equal quarterly installments starting three months after December 22, 2025, contingent upon continued service as a non-employee director. The filing also includes a Power of Attorney document, dated January 7, 2025, authorizing certain individuals at Minerva Neurosciences to execute insider trading forms (Forms 3, 4, and 5) on behalf of the undersigned. This authorization remains effective until reporting requirements cease, revocation, or the attorney-in-fact is no longer employed by the company. The transaction code "A" indicates the acquisition of the option, and the post-transaction shares owned are 50,000.