Form 3 Filing and Power of Attorney for Sanford Jay Siegel

This filing contains two parts: a Form 3, which reports initial beneficial ownership of securities, and a Power of Attorney document. The Form 3, filed on April 9, 2026, pertains to MDxHealth SA and indicates that Sanford Jay Siegel, a director, was granted an option to purchase 10,000 ordinary shares at $2.18 per share, vesting in full on the date of the annual general shareholders' meeting following the grant year. The Power of Attorney, dated March 4, 2026, designates Mark Busch and others as attorneys-in-fact for Sanford Jay Siegel. This grants them the authority to file necessary documents with the SEC, including Forms 3, 4, 5, and other beneficial ownership reports, utilizing the EDGAR system. The attorneys-in-fact are empowered to manage the EDGAR account, obtain information on equity security transactions, and act on behalf of Mr. Siegel regarding SEC filings. This Power of Attorney revokes previous ones and remains effective until Mr. Siegel is no longer required to file such reports.