Janus Henderson Group plc Acquires 5.5% Passive Stake in Edgewise Therapeutics, Inc.

On May 15, 2026, Janus Henderson Group plc filed a Schedule 13G with the SEC, reporting a new passive ownership stake in Edgewise Therapeutics, Inc. (EWTX). As of the event date on March 31, 2026, the investment firm disclosed beneficial ownership of 5,915,556 shares of common stock, representing 5.5% of the company's outstanding shares. Janus Henderson Group plc serves as the ultimate parent company for several SEC-registered investment advisers, including Janus Henderson Investors US LLC and Janus Henderson Investors UK Limited, which exercise investment and voting discretion over the shares on behalf of various managed portfolios. The filing indicates that the shares are held in the ordinary course of business and not for the purpose of changing or influencing the control of the issuer. The firm reported shared voting and dispositive power over the full 5,915,556 shares, while disclaiming direct ownership of dividends or sale proceeds, which belong to the underlying managed portfolios. This filing marks an increase from a previously reported 0% ownership level.