Monia Brett P plan to sell securities of IONIS PHARMACEUTICALS INC under Form 144

Monia Brett P filed Form 144 to notify SEC of plan to sell 100000 units of IONIS PHARMACEUTICALS INC securities around 2026-05-13, with aggregate market value of $7,801,300.00. The total outstanding units is 165262556.0. The amount planned to be sold represents 0.06% of total outstanding units; Recent transactions in past 3 months include: On 03/09/2026, sold 126670 units for $9525059.00; On 03/10/2026, sold 34103 units for $2589144.00;