Form 4 Filing for Genprex, Inc.

Jose Antonio Moreno Toscano, a director at Genprex, Inc., acquired 9,000 shares of Common Stock on December 22, 2025, with a transaction price of $0.00. This acquisition was part of an award of Restricted Stock Units (RSUs) under the company's 2018 Equity Incentive Plan. The RSUs vest fully on the earlier of August 15, 2026, or the day before the company's next annual stockholders' meeting, provided the recipient continues to serve as a Service Provider. Vested RSUs will be settled in shares of common stock on a one-to-one basis. Following this transaction and a 1-for-50 reverse stock split effective October 21, 2025, Mr. Toscano beneficially owns 9,157 shares of Common Stock. This filing is Form 4, indicating a change in beneficial ownership.