Form 4 Filing by Genprex, Inc. - Officer/Director Stock Transaction

This filing details a stock transaction by Brent Longnecker, a director at Genprex, Inc. On December 22, 2025, Longnecker acquired 9,000 shares of Common Stock under the Genprex, Inc. 2018 Equity Incentive Plan. These shares will vest on the earlier of August 15, 2026, or the day prior to the company's next annual meeting, provided continued service as a Service Provider. The vesting event will result in the issuance of shares of the Company's common stock on a one-to-one basis. Following this transaction, Longnecker beneficially owns 9,165 shares. This post-transaction figure accounts for a 1-for-50 reverse stock split effected on October 21, 2025. An additional 10 shares are held indirectly through Longnecker Associates Ltd.