Power of Attorney for Section 16 Reporting Obligations

This filing details a Power of Attorney granted by Vikram Karnani, a director of Dyne Therapeutics, Inc., to John Cox, Erick Lucera, Dan Wilson, and Ron Caponigro. The attorneys-in-fact are authorized to execute and file Forms 3, 4, and 5, including amendments, with the SEC on behalf of Mr. Karnani, in accordance with Section 16 of the Securities Exchange Act of 1934. This authorization includes obtaining necessary information about the company's securities from third parties and performing any actions deemed beneficial or legally required. The Power of Attorney remains in effect until Mr. Karnani is no longer subject to these reporting requirements or until it is revoked in writing. It is explicitly stated that the attorneys-in-fact and the company are not assuming Mr. Karnani's responsibilities or liabilities related to Section 16 compliance or profit disgorgement.