FMR LLC Significantly Reduces Stake in Day One Biopharmaceuticals to Below 5%

FMR LLC and Abigail P. Johnson have filed an amendment (Amendment No. 6) to their Schedule 13G regarding their holdings in Day One Biopharmaceuticals Inc (DAWN). As of the event date on March 31, 2026, the filers reported a significant reduction in their position, now holding 23,639.69 shares of common stock. This represents a 0.0% ownership stake in the company, indicating that their holdings have fallen below the 5% reporting threshold. The filing specifies that FMR LLC holds sole dispositive power over all 23,639.69 shares but maintains sole voting power over only 4,883 shares. Abigail P. Johnson, through her control of FMR LLC, is also deemed to have dispositive power over the total shares. The securities were acquired in the ordinary course of business and not for the purpose of influencing or changing control of the issuer. This filing follows a series of previous amendments and reflects the filers' exit from a substantial ownership position in the biopharmaceutical company.