Form 4 Filing for CRISPR Therapeutics AG - Officer/Director Stock Transaction

This filing details a transaction by Samarth Kulkarni, Chief Executive Officer and Director of CRISPR Therapeutics AG (CRSP). On December 18, 2025, Mr. Kulkarni disposed of 30,000 common shares with a transaction price of $0.00 per share. This transaction was coded as 'G' (likely indicating a gift or grant) and resulted in a post-transaction share ownership of 224,201 shares. Following this transaction, Mr. Kulkarni's total indirect ownership of common shares, held through 'The Kulkarni 2023 GRAT', amounts to 85,622 shares. The filing was signed by Samarth Kulkarni on December 22, 2025.