Form 4 Filing for Clene Inc.

This filing details transactions by Ugwumba Chidozie, a 10% owner of Clene Inc. On December 19, 2025, 5,582 shares of Common Stock were disposed of at a price of $6.45 per share, resulting in 387,568 shares remaining. Subsequently, on December 22, 2025, an additional 4,367 shares of Common Stock were disposed of at $6.54 per share, leaving 383,201 shares. These transactions were made by Symbiosis II, LLC, indicating indirect ownership.