FMR LLC Increases Stake in Caris Life Sciences Inc to 10.8%

FMR LLC has filed a Schedule 13G/A with the SEC, reporting a significant increase in its stake in Caris Life Sciences Inc (CAI). As of the event date on March 31, 2026, FMR LLC beneficially owns 30,631,858 shares of common stock, representing 10.8% of the company. This is a substantial increase from the previously reported position of 14,217,768 shares. The filing indicates that Abigail P. Johnson, as a director and chairman of FMR LLC, may be deemed to have a controlling influence over the company. The shares are held primarily for investment purposes in the ordinary course of business, with FMR LLC exercising sole dispositive power over the entire position and sole voting power over 30,592,295 shares. The total value of the holding is estimated at approximately $582.3 million. This amendment reflects FMR LLC's growing conviction in Caris Life Sciences, a biotechnology firm focused on precision medicine.